Evidence map›Paper›PMID 30378065›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Orthotopic Pancreatic Tumor Mouse Models of Liver Metastasis.

George Zhang, Yi-Chieh Nancy Du

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. A Metal-Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
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  7. Article
  8. Article
  9. Pre-clinical Models of Metastasis in Pancreatic Cancer.Frontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

George ZhangDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Yi-Chieh Nancy DuDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. nad2012@med.cornell.edu.
Cornell University · USWeill Cornell Medicine · US

Funding

Beyond apoptosis, Bcl-xL in tumor metastasisR01CA204916 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI DU, YI-CHIEH NANCY · 2017 to 2021
$2.0M
NCI NIH HHS R01 CA204916
6 · The paper itself

Abstract

The survival from pancreatic cancer is poor because most patients are diagnosed after the cancer has metastasized. Liver is the most common site of pancreatic cancer metastasis. Orthotopic mouse models of liver metastasis by intrasplenically injecting the pancreatic tumor cells are useful in studying the molecular mechanisms of metastasis and evaluating therapeutic regimens.

Indexed as

AnimalsCell Culture TechniquesCell Line, TumorCulture Media, ConditionedHumansLiverLiver NeoplasmsMiceMice, Inbred NODPancreatic NeoplasmsXenograft Model Antitumor AssaysCulture Media, ConditionedIntrasplenic injectionLiverMetastasisMouse modelOrthotopicPancreatic cancerSplenectomy

Identifiers

PMID30378065
PMCPMC6800204
OpenAlexW2899468997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.