Evidence map›Paper›PMID 30378003›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2019

Invasive Neuromodulation for the Treatment of Pediatric Epilepsy.

Laureen D Hachem, Han Yan, George M Ibrahim

Open access · bronzeAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Neurostimulation treatments for epilepsy: Deep brain stimulation, responsive neurostimulation and vagus nerve stimulation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. A New Era for Surgical Neurotherapeutics.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laureen D HachemDivision of Neurosurgery, Hospital for Sick Children, Department of Surgery, University of Toronto, 1503 555 University Ave., Toronto, ON, M5G 1X8, Canada.
Han YanDivision of Neurosurgery, Hospital for Sick Children, Department of Surgery, University of Toronto, 1503 555 University Ave., Toronto, ON, M5G 1X8, Canada.
George M IbrahimDivision of Neurosurgery, Hospital for Sick Children, Department of Surgery, University of Toronto, 1503 555 University Ave., Toronto, ON, M5G 1X8, Canada. george.ibrahim@sickkids.ca.
SickKids Foundation · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromodulatory strategies are increasingly adopted for the treatment of intractable epilepsy in children. These encompass a wide range of treatments aimed at externally stimulating neural circuitry in order to decrease seizure frequency. In the current review, the authors discuss the evidence for invasive neuromodulation, namely vagus nerve and deep brain stimulation in affected children. Putative mechanisms of action and biomarkers of treatment success are explored and evidence of the efficacy of invasive neuromodulation is highlighted.

Indexed as

ChildDeep Brain StimulationDrug Resistant EpilepsyHumansVagus Nerve StimulationBiomarkersdeep brain stimulationepilepsyseizuresvagus nerve stimulation

Identifiers

PMID30378003
PMCPMC6361060
OpenAlexW2899076600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.