Evidence map›Paper›PMID 30377975›Full record

ReviewBiophysical reviews2018

Evolution of research on cellular motility over five decades.

Thomas D Pollard

Abstract readReview
In one paragraph

Review in Biophysical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Thomas D PollardDepartments of Molecular Cellular and Developmental Biology, Yale University, PO Box 208103, New Haven, CT, 06520-8103, USA. thomas.pollard@yale.edu.ORCID http://orcid.org/0000-0002-1785-2969

Funding

MOLECULAR MECHANISMS OF CELLULAR MOTILITYR01GM026338 · NIGMS · YALE UNIVERSITY · PI POLLARD, THOMAS D. · 1985 to 2020
$9.8M
Mechanism of cytokinesis in fission yeastR01GM026132 · NIGMS · YALE UNIVERSITY · PI POLLARD, THOMAS D. · 1985 to 2021
$8.8M
NIGMS NIH HHS R01GM026132NIGMS NIH HHS R01 GM026338NIGMS NIH HHS R01GM026338
6 · The paper itself

Abstract

This short review traces how our knowledge of the molecular mechanisms of cellular movements originated and developed over the past 50 years. Work on actin-based and microtubule-based movements developed in different ways, but in both fields, the discovery of the key proteins drove progress. Starting from an inventory of zero molecules in 1960, both fields matured spectacularly, so we now know the atomic structures of the important proteins, understand the kinetics and thermodynamics of their interactions, have documented how the molecules behave in cells, and can test theories with molecularly explicit computer simulations of cellular processes.

Indexed as

ActinDyneinKinesinMyosinTubulin

Identifiers

PMID30377975
PMCPMC6297086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.