Evidence map›Paper›PMID 30377944›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2018

AAV-Vectored Fms-Related Tyrosine Kinase 3 Ligand Inhibits CD34

Lijun Ling, Xian Tang, Xiuyan Huang, Jingjing Li, Hui Wang, Zhiwei Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lijun LingAIDS Institute and Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, L5-45, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Xian TangUniversity of Hong Kong AIDS Institute-Shenzhen Research Laboratory, Guangdong Key Laboratory of Emerging Infectious Diseases and Shenzhen Key Laboratory of Infection and Immunity, Shenzhen Third People's Hospital, Shenzhen, People's Republic of China.
Xiuyan HuangAIDS Institute and Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, L5-45, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Jingjing LiAIDS Institute and Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, L5-45, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Hui WangUniversity of Hong Kong AIDS Institute-Shenzhen Research Laboratory, Guangdong Key Laboratory of Emerging Infectious Diseases and Shenzhen Key Laboratory of Infection and Immunity, Shenzhen Third People's Hospital, Shenzhen, People's Republic of China.
Zhiwei ChenAIDS Institute and Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, L5-45, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China. zchenai@hku.hk.
University of Hong Kong · HKShenzhen Third People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humanized mice have become useful animal models for HIV/AIDS. Since NOD.Cg-Prkdc scid Il2rgtm1Wjl/SzJ (NSG) mice allow the engraftment of primary human immune cells, we aim to determine the role of human Fms-related tyrosine kinase 3 ligand (hFlt3L), a major growth factor for dendritic cells (DCs), in regulating the differentiation of cord blood-derived CD34

Indexed as

AdenoviridaeAnimalsAntigens, CD34fms-Like Tyrosine Kinase 3Genetic VectorsHEK293 CellsHumansLeukocytes, MononuclearMiceMice, Inbred NODMice, TransgenicReactive Oxygen SpeciesStem CellsStem Cell TransplantationAntigens, CD34FLT3 protein, humanfms-Like Tyrosine Kinase 3Reactive Oxygen SpeciesCD34+ progenitor cellsFms-related tyrosine kinase 3 ligandhumanized mousemyeloid-derived immune suppressive cells

Identifiers

PMID30377944
OpenAlexW2898756782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.