Evidence map›Paper›PMID 30377926›Full record

SynthesisJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2019

Percutaneous ventricular assist device in ventricular tachycardia ablation: a systematic review and meta-analysis.

Mohit K Turagam, Venkat Vuddanda, Scott Koerber, Jalaj Garg, Bharath Yarlagadda, Tawseef Dar, Arash Aryana, Luigi Di Biase, Andrea Natale, Dhanunjaya Lakkireddy

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Preemptive mechanical circulatory support in ventricular tachycardia ablation: A systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Percutaneous mechanical support in catheter ablation of ventricular arrhythmias: hype or hope?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Complications of catheter ablation for ventricular tachycardia.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Mohit K TuragamIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Venkat VuddandaHarvard Medical School, Boston, MA, USA.
Scott KoerberMedical University of South Carolina, Charleston, SC, USA.
Jalaj GargIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Bharath YarlagaddaKansas City Heart Rhythm Institute & Research Foundation, Overland Park, KS, 66221, USA.
Tawseef DarKansas City Heart Rhythm Institute & Research Foundation, Overland Park, KS, 66221, USA.
Arash AryanaMercy General Hospital and Dignity Health Heart and Vascular Institute, Sacramento, CA, USA.
Luigi Di BiaseMontefiore Medical Center, Bronx, NY, USA.
Andrea NataleTexas Cardiac Arrhythmia Institute, Austin, TX, USA.
Dhanunjaya LakkireddyKansas City Heart Rhythm Institute & Research Foundation, Overland Park, KS, 66221, USA. dlakkireddy@gmail.com.
Heart Rhythm Society · USIcahn School of Medicine at Mount Sinai · USHarvard University · USMedical University of South Carolina · USMercy General Hospital · USMontefiore Medical Center · USTexas Cardiac Arrhythmia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of compelling data regarding the benefit of percutaneous ventricular assist devices (PVAD) in patients undergoing ventricular tachycardia (VT) ablation. The study aims to conduct a meta-analysis comparing the safety and efficacy of PVAD versus no-PVAD (N-PVAD) during VT ablation.

methodsStudies meeting criteria were systematically reviewed. Baseline characteristics and clinical outcomes were extracted and analyzed. A meta-analysis was performed using random-effects model to calculate risk ratio (RR) and mean difference (MD) with 95% confidence interval (CI).

resultsThe meta-analysis included five retrospective, observational studies consisting of 2026 patients (PVAD group-284 patients versus N-PVAD group-1742 patients). The PVAD group was sicker with significantly higher VT storm, lower LVEF and greater proportion of NYHA class ≥ III than N-PVAD (p < 0.050). The acute procedural success [RR 0.95, 95% CI, (0.89-1.00), p = 0.070], VT recurrence [RR 0.94, 95% CI, (0.66-1.34), p = 0.740] and mortality [RR 1.28, 95% CI, (0.43-3.83), p = 0.660] were similar on follow-up between PVAD versus N-PVAD. PVAD group also had significantly higher complications [RR 1.83, 95% CI (1.21-2.76), p = 0.004] and longer fluoroscopy [MD + 7.31 min, 95% CI (0.91-13.71), p = 0.030] and procedure time [MD + 71.41 min, 95% CI (31.67-111.14), p < 0.001] than N-PVAD.

conclusionPatients receiving PVAD support during VT ablation were sicker with no significant difference in acute procedural success, VT recurrence, and mortality compared with N-PVAD. PVAD support was also associated with higher complications and longer fluoroscopy and procedure time. A prospective randomized controlled trial will identify if using PVAD support in unstable patients undergoing VT ablation will impact clinical outcomes.

Indexed as

Heart-Assist DevicesCatheter AblationHumansTachycardia, VentricularCatheter ablationECMOHemodynamic supportImpellaPercutaneous ventricular assist deviceTandem heartVentricular tachycardia

Identifiers

PMID30377926
OpenAlexW2899118168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.