Evidence map›Paper›PMID 30377873›Full record

ArticleEuropean radiology experimental2018

Generative models: an upcoming innovation in musculoskeletal radiology? A preliminary test in spine imaging.

Fabio Galbusera, Tito Bassani, Gloria Casaroli, Salvatore Gitto, Edoardo Zanchetta, Francesco Costa, Luca Maria Sconfienza

Abstract read
In one paragraph

Article in European radiology experimental, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. [Deep learning method for magnetic resonance imaging fluid-attenuated inversion recovery image synthesis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
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  11. A practical guide to the development and deployment of deep learning models for the orthopedic surgeon: part II.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
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  13. Artificial Intelligence in Spinal Imaging: Current Status and Future Directions.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabio GalbuseraLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy. fabio.galbusera@grupposandonato.it.ORCID http://orcid.org/0000-0003-1826-9190
Tito BassaniLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy.
Gloria CasaroliLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy.
Salvatore GittoUnit of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy.
Edoardo ZanchettaUnit of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy.
Francesco CostaDepartment of Neurosurgery, Humanitas Clinical and Research Hospital, Via Manzoni 56, 20089, Rozzano, Italy.
Luca Maria SconfienzaUnit of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Galeazzi, via Galeazzi 4, 20161, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep learning is a ground-breaking technology that is revolutionising many research and industrial fields. Generative models are recently gaining interest. Here, we investigate their potential, namely conditional generative adversarial networks, in the field of magnetic resonance imaging (MRI) of the spine, by performing clinically relevant benchmark cases.

methodsFirst, the enhancement of the resolution of T2-weighted (T2W) images (super-resolution) was tested. Then, automated image-to-image translation was tested in the following tasks: (1) from T1-weighted to T2W images of the lumbar spine and (2) vice versa; (3) from T2W to short time inversion-recovery (STIR) images; (4) from T2W to turbo inversion recovery magnitude (TIRM) images; (5) from sagittal standing x-ray projections to T2W images. Clinical and quantitative assessments of the outputs by means of image quality metrics were performed. The training of the models was performed on MRI and x-ray images from 989 patients.

resultsThe performance of the models was generally positive and promising, but with several limitations. The number of disc protrusions or herniations showed good concordance (κ = 0.691) between native and super-resolution images. Moderate-to-excellent concordance was found when translating T2W to STIR and TIRM images (κ ≥ 0.842 regarding disc degeneration), while the agreement was poor when translating x-ray to T2W images.

conclusionsConditional generative adversarial networks are able to generate perceptually convincing synthetic images of the spine in super-resolution and image-to-image translation tasks. Taking into account the limitations of the study, deep learning-based generative methods showed the potential to be an upcoming innovation in musculoskeletal radiology.

Indexed as

Lumbar vertebraeMachine learning (deep learning)Magnetic resonance imagingNeural network (computer)X-rays

Identifiers

PMID30377873
PMCPMC6207611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.