Evidence map›Paper›PMID 30377868›Full record

ArticleNanoscale research letters2018

Antioxidant Potential of Artemisia capillaris, Portulaca oleracea, and Prunella vulgaris Extracts for Biofabrication of Gold Nanoparticles and Cytotoxicity Assessment.

Eun-Young Ahn, You Jeong Lee, Jisu Park, Pusoon Chun, Youmie Park

Abstract read
In one paragraph

Article in Nanoscale research letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Cytotoxic Effects ofAnti-cancer agents in medicinal chemistry · 2025
    Article
  3. Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  4. Article
  5. Bio-Fabrication of Silver Nanoparticles UsingPlants (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Review
  8. Effects ofMolecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eun-Young AhnCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
You Jeong LeeCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
Jisu ParkCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
Pusoon ChunCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
Youmie ParkCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea. youmiep@inje.ac.kr.

Funding

Inje University 2017 Inje University research grant
6 · The paper itself

Abstract

Three aqueous plant extracts (Artemisia capillaris, Portulaca oleracea, and Prunella vulgaris) were selected for the biofabrication of gold nanoparticles. The antioxidant activities (i.e., free radical scavenging activity, total phenolic content, and reducing power) of the extracts and how these activities affected the biofabrication of gold nanoparticles were investigated. P. vulgaris exerted the highest antioxidant activity, followed by A. capillaris and then P. oleracea. P. vulgaris was the most efficient reducing agent in the biofabrication process. Gold nanoparticles biofabricated by P. vulgaris (PV-AuNPs) had a maximum surface plasmon resonance of 530 nm with diverse shapes. High-resolution X-ray diffraction analysis showed that the PV-AuNPs had a face-centered cubic structure. The reaction yield was estimated to be 99.3% by inductively coupled plasma optical emission spectroscopy. The hydrodynamic size was determined to be 45 ± 2 nm with a zeta potential of - 13.99 mV. The PV-AuNPs exerted a dose-dependent antioxidant activity. Remarkably, the highest cytotoxicity of the PV-AuNPs was observed against human colorectal adenocarcinoma cells in the absence of fetal bovine serum, while for human pancreas ductal adenocarcinoma cells, the highest cytotoxicity was observed in the presence of fetal bovine serum. This result demonstrates that P. vulgaris extract was an efficient reducing agent for biofabrication of gold nanoparticles exerting cytotoxicity against cancer cells.

Indexed as

Antioxidant activityArtemisia capillarisBiofabricationCytotoxicityGold nanoparticlesPlant extractsPortulaca oleraceaProtein coronaPrunella vulgaris

Identifiers

PMID30377868
PMCPMC6207604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.