Evidence map›Paper›PMID 30377755›Full record

Trial reportSurgical endoscopy2019

A randomized clinical trial comparing the initial vascular approach to the inferior mesenteric vein versus the inferior mesenteric artery in laparoscopic surgery of rectal cancer and sigmoid colon cancer.

Pere Planellas, Helena Salvador, Ramon Farrés, Núria Gómez, David Julià, Júlia Gil, Marcel Pujadas, Franco Marinello, Lídia Cornejo, Antoni Codina

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pere PlanellasSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain. planellasp@gmail.com.ORCID http://orcid.org/0000-0003-2799-3105
Helena SalvadorSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Ramon FarrésSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Núria GómezSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
David JuliàSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Júlia GilSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Marcel PujadasSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Franco MarinelloSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.
Lídia CornejoGirona Biomedical Research Foundation, Girona, Spain.
Antoni CodinaSection of Colorectal Surgery, Department of General and Digestive Surgery, Dr Josep Trueta University Hospital, France Avenue s/n, 17007, Girona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe inferior mesenteric artery approach with a selective lateral splenic flexure mobilization is the most widely used initial step in laparoscopic rectal and left colon surgery. Surgery started through the inferior mesenteric vein (IMV) with systematic medial mobilization (MM) has some theoretical advantages that have never been analyzed in a clinical trial. The aim of this study was to compare the two techniques with regards to surgical technique variables (conversion, surgical time, bleeding, morbidity, and mortality) and pathological outcomes.

methodsA single-blinded, randomized, controlled trial of patients operated electively by laparoscopic with curative intention for rectal or sigmoid cancer was performed at a single, specialized colorectal surgery department from April 2016 to October 2017.

results49 patients were included in each group. There were no statistical differences in patient demographics between the two approaches. Pathological outcomes did not differ between the two groups. Intra-operative characteristics showed a higher conversion rate in patients in which the inferior mesenteric artery was dissected first (p = 0.031). The artery approach also increased intra-operative bleeding (p = 0.049), but there were no differences regarding operative time. On multivariate analysis, the artery approach was associated with a higher risk of conversion (OR 8.68; p = 0.050). Post-operatory complications did not differ between artery and vein dissection.

conclusionsIn our study, the initial approach by the IMV with a systematic MM of the splenic flexure has allowed us to reduce the conversion rate without increasing complications or the surgical time. No differences were observed in the pathological results. Both approaches seem to be safe and effective and well-trained laparoscopic surgeons should have the two techniques available to them for use as needed.

Indexed as

Blood Loss, SurgicalDissectionFemaleHumansLaparoscopyMaleMesenteric Artery, InferiorMesenteric VeinsMiddle AgedOperative TimePostoperative ComplicationsRectal NeoplasmsSigmoid NeoplasmsSingle-Blind MethodColorectal cancerInferior mesenteric veinRectal cancerSplenic colon flexureVascular approach

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.