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ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2019

Is low dose radiotherapy an effective treatment for Baker's cyst?

Matthias G Hautmann, Ernst-Michael Jung, Lukas P Beyer, Christoph Süß, Felix Steger, Markus Weber, Fabian Pohl, Oliver Kölbl, Franz Josef Putz

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04424628 naunknown statusnot on this map

Three vs Six Gy in Gonarthrosis and Coxarthrosis. Non Inferiority Study

TypeinterventionalSponsorFundacion GenesisCareRan2019 to 2023Enrolled338ConditionsGonarthrosis, CoxarthrosisArmsLow dose radiotherapy A, Low dose radiotherapy B
NCT06079684 nacompletednot on this mapstarted 2022, after this paper: background citation

Clinical Evidence Regarding The Dynamic of Baker Cyst Dimensions After Intermittent Vacuum Therapy As Rehabilitation Treatment In Patients With Knee Osteoarthritis

TypeinterventionalSponsorBalnear and Rehabilitation Sanatorium TechirghiolRan2022 to 2022Enrolled65ConditionsBaker Cyst, Knee OsteoarthritisArmsIntermittent vacuum therapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Radiotherapy for osteoarthritis-an analysis of 295 joints treated with a linear accelerator.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  4. Radiotherapy for osteoarthritis of the ankle and tarsal joints-analysis of 66 joints.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  5. Re-irradiation for osteoarthritis-retrospective analysis of 217 joints.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Matthias G HautmannDepartment of Radiotherapy, University of Regensburg, Regensburg, Germany. matthias.hautmann@ukr.de.
Ernst-Michael JungDepartment of Radiology, University of Regensburg, Regensburg, Germany.
Lukas P BeyerDepartment of Radiology, University of Regensburg, Regensburg, Germany.
Christoph SüßDepartment of Radiotherapy, University of Regensburg, Regensburg, Germany.
Felix StegerDepartment of Radiotherapy, University of Regensburg, Regensburg, Germany.
Markus WeberDepartment of Orthopaedics, Asklepios Klinikum Bad Abbach, University of Regensburg, Bad Abbach, Germany.
Fabian PohlDepartment of Radiotherapy, University of Regensburg, Regensburg, Germany.
Oliver KölblDepartment of Radiotherapy, University of Regensburg, Regensburg, Germany.
Franz Josef PutzDepartment of Nephrology, University of Regensburg, Regensburg, Germany.
University of Regensburg · DEAsklepios Kliniken Bad Abbach · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOsteoarthritis of the knee is a common disease, often associated with a Baker's cyst. Besides osteoarthritis, also other joint pathologies of the knee can be causative for a Baker's cyst. Radiotherapy is known to be an effective treatment for osteoarthritis, with an anti-inflammatory effect. As the excessive production of synovia usually is associated with intraarticular inflammation, our hypothesis was that radiotherapy might positively influence the synovial production and reduce the volume of a Baker's cyst. MATERIALS AND

methodsWe performed a prospective trial, including 20 knees receiving radiotherapy for knee arthritis. Besides documentation of NRS (numeric rating scale), WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) score and Knee Society Score, the volume of the Baker's cyst was calculated for a short- (6 to 12 weeks) and long-term (9 to 12 months) follow-up. Ultrasonic volumetry was performed using an ultrasound device with a high-resolution multifrequency linear probe (6-9 MHz).

resultsLow-dose radiotherapy improved NRS, WOMAC score and Knee Society Score significantly. The mean volume of Baker's cyst decreased from 22.3 ml to 10.7 respectively 3.1 ml during follow-up. A decrease in volume of more than 25% compared to the baseline could be achieved for 75% of the patients in the short-term and 79% of the patients in the long-term follow up.

conclusionRadiotherapy of knee osteoarthritis is an effective treatment that decreases the volume of a Baker's cyst. Most patients respond to the treatment. Whether radiotherapy is an effective treatment for Baker's cyst without associated osteoarthritis has to be further examined.

Indexed as

Radiotherapy DosageAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedOsteoarthritis, KneePopliteal CystProspective StudiesTreatment OutcomeUltrasonographyBaker’s cystKnee arthritisOsteoarthritis of the KneePopliteal cystRadiotherapy

Identifiers

PMID30377698
OpenAlexW2899456411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.