Evidence map›Paper›PMID 30377546›Full record

ArticleWestern Pacific surveillance and response journal : WPSAR

Viral load suppression and acquired HIV drug resistance in adults receiving antiretroviral therapy in Viet Nam: results from a nationally representative survey.

Vu Quoc Dat, Bui Duc Duong, Do Thi Nhan, Nguyen Huu Hai, Nguyen Thi Lan Anh, Huynh Hoang Khanh Thu, Tran Ton, Luong Que Anh, Nguyen Tuan Nghia, Nguyen Vu Thuong and 10 more

Abstract read
In one paragraph

Article in Western Pacific surveillance and response journal : WPSAR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Vu Quoc DatDepartment of Infectious Diseases, Hanoi Medical University, Hanoi, Vietnam.
Bui Duc DuongVietnam Authority of HIV/AIDS Control, Hanoi, Vietnam.
Do Thi NhanVietnam Authority of HIV/AIDS Control, Hanoi, Vietnam.
Nguyen Huu HaiVietnam Authority of HIV/AIDS Control, Hanoi, Vietnam.
Nguyen Thi Lan AnhNational Institute of Hygiene Epidemiology (NIHE), Hanoi, Vietnam.
Huynh Hoang Khanh ThuPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tran TonPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Luong Que AnhPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nguyen Tuan NghiaNational Institute of Hygiene Epidemiology (NIHE), Hanoi, Vietnam.
Nguyen Vu ThuongPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Khuu Van NghiaPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tran Thi Minh TamNational Institute of Hygiene Epidemiology (NIHE), Hanoi, Vietnam.
Tran Phuc HauPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nguyen Duy PhucPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Vu Xuan ThinhPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nguyen Tran HienNational Institute of Hygiene Epidemiology (NIHE), Hanoi, Vietnam.
Truong Thi Xuan LienPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Silvia BertagnolioWorld Health Organization, Geneva, Switzerland.
Nguyen Thi Thuy VanWorld Health Organization Viet Nam Country Office, Hanoi, Vietnam.
Masaya KatoWorld Health Organization Viet Nam Country Office, Hanoi, Vietnam.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveThe purpose of this survey was to estimate the prevalence of viral load (VL) suppression and emergence of HIV drug resistance (HIVDR) among individuals receiving antiretroviral therapy (ART) for 36 months or longer in Viet Nam using a nationally representative sampling method.

methodsThe survey was conducted between May and August 2014 using a two-stage cluster design. Sixteen ART clinics were selected using probability proportional to proxy size sampling, and patients receiving ART for at least 36 months were consecutively enrolled. Epidemiological information and blood specimens were collected for HIV-1 VL and HIVDR testing; HIVDR was defined by the Stanford University HIVDR algorithm.

resultsOverall, 365 eligible individuals were recruited with a mean age of 38.2 years; 68.4% were men. The mean time on ART was 75.5 months (95% confidence interval [CI]: 69.0-81.9 months), and 93.7% of the patients were receiving non-nucleoside reverse transcriptase inhibitor-based regimens. Of the 365 individuals, 345 (94.7%, 95% CI: 64.1-99.4%) had VL below 1000 copies/mL and 19 (4.6%, 95% CI: 2.8--7.5) had HIVDR mutations. DISCUSSION: Our nationally representative survey found a high level of VL suppression and a low prevalence of HIVDR among individuals who received ART for at least 36 months in Viet Nam. Continued surveillance for HIVDR is important for evaluating and improving HIV programs.

Indexed as

Drug Resistance, ViralAdultAnti-Retroviral AgentsFemaleHIV InfectionsHumansMaleSurveys and QuestionnairesTime FactorsTreatment OutcomeVietnamViral LoadAnti-Retroviral Agents

Identifiers

PMID30377546
PMCPMC6194224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.