Evidence map›Paper›PMID 30377274›Full record

ArticlemBio2018

The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources.

Gemma Perez-Samper, Bram Cerulus, Abbas Jariani, Lieselotte Vermeersch, Nuria Barrajón Simancas, Markus M M Bisschops, Joost van den Brink, Daniel Solis-Escalante, Brigida Gallone, Dries De Maeyer and 6 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Foods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Microbial ecology of fermented foods.FEMS yeast research · 2026
    Review
  6. Article
  7. Review
  8. The evolution of thermal performance curves in response to rising temperatures across the model genus yeast.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Gemma Perez-Samper *VIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Bram Cerulus *VIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Abbas JarianiVIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Lieselotte VermeerschVIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Nuria Barrajón SimancasDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands.
Markus M M BisschopsDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands.
Joost van den BrinkDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands.
Daniel Solis-EscalanteDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands.
Brigida GalloneVIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Dries De MaeyerCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Elise van BaelVIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Tom WenseleersLaboratory of Socioecology and Social Evolution, Department of Biology, KU Leuven, Leuven, Belgium.
Jan MichielsVIB - KU Leuven Center for Microbiology, Leuven, Belgium.
Kathleen MarchalCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Pascale Daran-LapujadeDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands p.a.s.daran-lapujade@tudelft.nl Kevin.Verstrepen@kuleuven.vib.be.ORCID 0000-0002-4097-7831
Kevin J VerstrepenVIB - KU Leuven Center for Microbiology, Leuven, Belgium p.a.s.daran-lapujade@tudelft.nl Kevin.Verstrepen@kuleuven.vib.be.ORCID 0000-0002-3077-6219
VIB-KU Leuven Center for Microbiology · BEDelft University of Technology · NLKU Leuven · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When faced with environmental changes, microbes often enter a temporary growth arrest during which they reprogram the expression of specific genes to adapt to the new conditions. A prime example of such a lag phase occurs when microbes need to switch from glucose to other, less-preferred carbon sources. Despite its industrial relevance, the genetic network that determines the duration of the lag phase has not been studied in much detail. Here, we performed a genome-wide Bar-Seq screen to identify genetic determinants of the

Indexed as

Adaptation, PhysiologicalGene Expression Regulation, FungalAerobiosisAnaerobiosisElectron Transport Chain Complex ProteinsGalactoseGlucoseSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsElectron Transport Chain Complex ProteinsGalactoseGlucoseSaccharomyces cerevisiae ProteinsCrabtree effectdiauxic growthlag phaserespirationSaccharomyces cerevisiae

Identifiers

PMID30377274
PMCPMC6212832
OpenAlexW2898796967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.