ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018
[Value of serum alkaline phosphatase for predicting 2-year fracture in patients with chronic kidney disease on dialysis].
Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors at 1 institution in 1 country.
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Abstract
objectiveTo explore the value of baseline serum alkaline phosphatase (ALP) for predicting 2-year fracture in patients with chronic kidney disease (CKD) on maintenance dialysis.
methodsA total of 139 patients with CKD undergoing maintenance dialysis in our hospital were enrolled in this study. According to the median serum ALP level, the patients were divided into high ALP and low ALP groups. The demographic and clinical data of the patients including dialysis duration, serum calcium level, serum phosphorus level, and serum intact parathyroid hormone level were recorded, and their bone mineral density of the femur and the lumbar spine was measured using dual energy X-ray absorptiometry. The patients were followed up for 2 years and fracture events were recorded. The risk factors of fracture were analyzed using logistic regression analysis, and their predictive value for fracture was analyzed using receiver-operating characteristic (ROC) curve.
resultsThe mean baseline serum ALP level was 132.55±167.68 U/L in these patients, significantly higher than that in the normal population (
conclusionsSerum ALP may serve as a good indicator for predicting 2-year fractures in patients with CKD on maintenance dialysis.
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