Evidence map›Paper›PMID 30377109›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018

[Maternal neutrophil-to-lymphocyte ratio as a prognostic biomarker for placental inflammatory response in late pregnancy].

Yuwen Qiu, Yuwen Wen, Guang Li, Zixin Tao, Xinyue Yan, Nailiang Zang, Mei Zhong, Qitao Huang

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuwen QiuDepartment of Obstetrics and Gynecology, Nanfang Hospital, Guangzhou 510515, China.
Yuwen WenFirst Clinical Medical College of Southern Medical University, Guangzhou 510515, China.
Guang LiDepartment of Obstetrics and Gynecology, Nanfang Hospital, Guangzhou 510515, China.
Zixin TaoDepartment of Obstetrics and Gynecology, Nanfang Hospital, Guangzhou 510515, China.
Xinyue YanFirst Clinical Medical College of Southern Medical University, Guangzhou 510515, China.
Nailiang ZangFirst Clinical Medical College of Southern Medical University, Guangzhou 510515, China.
Mei ZhongDepartment of Obstetrics and Gynecology, Nanfang Hospital, Guangzhou 510515, China.
Qitao HuangDepartment of Obstetrics and Gynecology, Nanfang Hospital, Guangzhou 510515, China.
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the association between maternal serum neutrophil-lymphocyte ratio (NLR) and placental inflammatory response (PIR) in late pregnancy.

methodsWe retrospectively analyzed the clinical and follow-up data of 478 pregnant women undergoing routine prenatal examination and delivery in our hospital in the year 2016. According to the placental pathological results, the women were divided into PIR group (238 cases) and control group (240 cases). The levels of serum inflammatory makers including leukocytes, neutrophils, lymphocytes, C-reactive protein (CRP) and NLR were compared between the two groups to analyze the association of these markers with PIR. Multivariate analysis was performed to identify the independent risk factors of PIR. Logistic regression model was established and the area under the receiver operating characteristic curve (ROC) was used for analyzing the prognostic value of these makers in late pregnancy.

resultsThe areas under the curve (AUC) of leukocytes, neutrophils, lymphocytes, CRP and NLR were 0.698 (95%

conclusionsAn increased NLR in late pregnancy can serve as an effective indicator for predicting the risk of PIR.

Indexed as

BiomarkersCase-Control StudiesChorioamnionitisC-Reactive ProteinFemaleHumansLeukocyte CountLymphocyte CountLymphocytesNeutrophilsPregnancyPrognosisRetrospective StudiesROC CurveBiomarkersC-Reactive Proteininflammationneutrophil-lymphocyte ratioplacenta

Identifiers

PMID30377109
PMCPMC6744194
OpenAlexW3024103220

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.