Evidence map›Paper›PMID 30377105›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018

[β2-nicotinic acetylcholine receptor promotes development of GABA

Chao Zheng, Yan Huang, Huanhuan Zhang, Yingying Zha, Mengya Wang

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chao ZhengCell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China.
Yan HuangCell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China.
Huanhuan ZhangCell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China.
Yingying ZhaCell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China.
Mengya WangCell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China.
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the role of β2-nicotinic acetylcholine receptor (β2-nAChR) in the development of γ- aminobutyric acid A type receptors (GABA

methodsThe hippocampal CA1 and CA3 pyramidal neurons were acutely isolated from β2-nAChR gene knockout (β2-KO group) mice. GABA currents in CA1 and CA3 pyramidal neurons were induced with the selective GABA

resultsThe mean E

conclusionsβ2-containing nAChRs may promote the functional maturation of GABA

Indexed as

AnimalsCA1 Region, HippocampalCA3 Region, HippocampalEvoked PotentialsGABA-A Receptor AgonistsGene Knockdown TechniquesHippocampusMiceMuscimolPatch-Clamp TechniquesPyramidal CellsReceptors, GABA-AReceptors, NicotinicGABA-A Receptor AgonistsMuscimolReceptors, GABA-AReceptors, Nicotinicequilibrium potential of muscimol-induced currentsgene knockouthippocampuskinetic indexesβ2-nicotinic acetylcholine receptorsγ-aminobutyric acid A type receptors

Identifiers

PMID30377105
PMCPMC6744193
OpenAlexW2897428969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.