Evidence map›Paper›PMID 30377098›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018

[Low-intensity pulsed ultrasound pretreatment inhibits HMGB1 expression and attenuates lung ischemia-reperfusion injury in rats

Liangchao Qu, Jinxiu Yan, Zhangjie Jiang, Zhiping Song, Foquan Luo, Qinghua Peng

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liangchao QuDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Jinxiu YanDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhangjie JiangDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhiping SongDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Foquan LuoDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Qinghua PengDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the effects of low-intensity pulsed ultrasound (LIPUS) pretreatment on pulmonary expression of high mobility group box-1 (HMGB1) in a rat model of lung ischemia-reperfusion (IR).

methodsThirty-two male SpragueDawley rats weighing 250-300 g were randomly divided (

resultsCompared with those in the sham-operated group, the W/D of the lung tissue, LPI, pathological scores, IL-1 and IL-6 contents in the lung tissue, and pulmonary HMGB1 expression all significantly increased in the other 3 groups (

conclusionsLIPUS preconditioning can reduce lung IR injury possibly by activating α7nAChR-dependent cholinergic anti-inflammatory pathway to reduce lung tissue HMGB1 expression.

Indexed as

Aconitinealpha7 Nicotinic Acetylcholine ReceptorAnimalsHMGB1 ProteinInterleukin-1Interleukin-6LungMaleNicotinic AntagonistsRandom AllocationRatsRats, Sprague-DawleyReperfusion InjuryUltrasonic TherapyUltrasonic WavesAconitinealpha7 Nicotinic Acetylcholine ReceptorHMGB1 ProteinInterleukin-1Interleukin-6methyllycaconitineNicotinic Antagonistshigh mobility group box-1ischemia and reperfusion injurylow intensity pulsed-ultrasoundα-7nAChR

Identifiers

PMID30377098
PMCPMC6744187
OpenAlexW3024790242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.