ArticleBMC pharmacology & toxicology2018
A rare case report of heavy dose colchicine induced acute kidney injury.
Article in BMC pharmacology & toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Poisoning-Induced Acute Kidney Injury: A Review.Medicina (Kaunas, Lithuania) · 2024Review
- Colchicine: the good, the bad, the ugly and how to minimize the risks.Rheumatology (Oxford, England) · 2024Article
- Colchicine Poisoning: A Rare Case.Cureus · 2023Article
- Skin donations after suicide by acute poisoning.Cell and tissue banking · 2023Article
- Colchicine poisoning treated with hemoperfusion and hemodialysis: A case report.Clinical case reports · 2022Article
- Progress in the management of acute colchicine poisoning in adults.Internal and emergency medicine · 2022Review
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColchicine is a natural alkaloid that is mainly used for the treatment of inflammatory diseases. Effective and toxic doses are very similar, but case reports of higher colchicine doses inducing acute toxicosis is rare. CASE PRESENTATION: A 19-year-old woman was sent to the emergency room for taking 80 colchicine tablets (0.5 mg per tablet) 44 h previously. The main physical symptom was abdominal pain. Following ingestion, the patient suffered multi-system failure including renal, respiratory, circulatory, and digestive. Continuous renal replacement therapy (CRRT) and other treatment measures were used to remove metabolic wastes and poisons, and to treat other complications. Renal function was restored after a series of treatments.
conclusionWe report a case of an acute kidney injury induced by an overdose of colchicine. CRRT and a series of related treatments were beneficial for the treatment of colchicine poisoning.
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