Evidence map›Paper›PMID 30376887›Full record

ArticleAlzheimer's research & therapy2018

Analysis of the risk and risk factors for injury in people with and without dementia: a 14-year, retrospective, matched cohort study.

Ruey Chen, Wu-Chien Chien, Ching-Chiu Kao, Chi-Hsiang Chung, Doresses Liu, Huei-Ling Chiu, Kuei-Ru Chou

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's research & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Ruey ChenDepartment of Nursing, Taipei Medical University-Shuang Ho Hospital, No.291, Zhongzheng Rd., Zhonghe District, Taipei, 23561, Taiwan.
Wu-Chien ChienDepartment of Medical Research, Tri-Service General Hospital, No.325, Section 2, Cheng-Kung Road, Neihu District, Taipei, 11490, Taiwan.
Ching-Chiu KaoSchool of Nursing, College of Nursing, Taipei Medical University, No.250, Wu-Hsing Street, Taipei, 11031, Taiwan.
Chi-Hsiang ChungSchool of Public Health, National Defense Medical Center, No.161, Section 6, Min-Chuan East Road, Neihu District, Taipei, 11490, Taiwan.
Doresses LiuDepartment of Nursing, Wan Fang Hospital, Taipei Medical University, No.111, Sec. 3, Xinglong Rd., Taipei, 11696, Taiwan.
Huei-Ling ChiuSchool of Gerontology Health Management, College of Nursing, Taipei Medical University, No.250, Wu-Hsing Street, Taipei, 11031, Taiwan.
Kuei-Ru ChouDepartment of Nursing, Taipei Medical University-Shuang Ho Hospital, No.291, Zhongzheng Rd., Zhonghe District, Taipei, 23561, Taiwan. kueiru@tmu.edu.tw.ORCID 0000-0002-4882-3503
Wan Fang Hospital · TWTaipei Medical University · TWTaipei Medical University Hospital · TWTaipei Medical University-Shuang Ho Hospital · TWTaiwan Nurses Association · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost previous studies on dementia and injuries have focused on a particular type of injury, and few studies have investigated overall injury in people with dementia. In this study, we investigated the risk factors and risk of overall injury, including the diagnosis, cause, and intentionality of injury, in people with and without dementia in Taiwan.

methodsWe collected relevant data between 2000 and 2013 from the National Health Insurance Research Database (NHIRD). Overall, 455,630 cases, consisting of 91,126 people with dementia and 364,504 people without dementia, were included in this study and we performed subgroup analysis. A multivariate Cox proportional hazards regression analysis was used to determine the risk of injuries.

resultsThe 14-year follow-up data showed that people with dementia had a higher risk of injury-related hospitalization than did people without dementia (19.92% vs 18.86%, hazard ratio (HR) = 1.070, p < 0.001). Regarding the cause of injury, people with dementia were more likely to be hospitalized due to suffocation (HR = 2.301, p < 0.001), accidental drug poisoning (HR = 1.485, p < 0.001), or falls (HR = 1.076, p < 0.001), and were less likely to be hospitalized due to suicide or self-inflicted injury (HR = 0.670, p < 0.001) or a traffic accident (HR = 0.510, p < 0.001) than were people without dementia. Subgroup analysis showed that people with dementia with any of the three subtypes of dementia were at a higher risk of homicide or abuse than were people without dementia (vascular dementia, HR = 2.079, p < 0.001; Alzheimer's disease, HR = 1.156, p < 0.001; other dementia, HR = 1.421, p < 0.001). The risk factors for overall injury included dementia diagnosis, female gender, age 65-74 years, and seeking medical attention for an injury within the past year.

conclusionPeople with dementia are at a higher risk of injury-related hospitalization than people without dementia. The results of this study provide a reference for preventing suffocation, drug poisoning, and falls in people with dementia. In addition, government agencies should pay attention to and intervene in cases of abuse suffered by people with dementia.

Indexed as

AgedAged, 80 and overDementiaFemaleHospitalizationHumansMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsWounds and InjuriesAbuseAccidental drug poisoningDementiaFallsInjurySuffocationSuicideTraffic

Identifiers

PMID30376887
PMCPMC6208020
OpenAlexW2899485850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.