Evidence map›Paper›PMID 30376849›Full record

Trial reportWorld journal of surgical oncology2018

Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study.

Gian Andrea Prevost, Manfred Odermatt, Markus Furrer, Peter Villiger

Open access · goldAbstract readClinical TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 7 pooled it
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  13. Quality assessment of surgery for colorectal cancer: Where do we stand?World journal of gastrointestinal surgery · 2024
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  15. Best Evidence for Each Surgical Step in Minimally Invasive Right Hemicolectomy: A Systematic Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gian Andrea PrevostDepartment of Surgery, Kantonsspital Graubünden, Loëstrasse 170, CH-7000, Chur, Switzerland. gianandreapre@hotmail.com.ORCID http://orcid.org/0000-0002-6041-3304
Manfred OdermattDepartment of Surgery, Kantonsspital Graubünden, Loëstrasse 170, CH-7000, Chur, Switzerland.
Markus FurrerDepartment of Surgery, Kantonsspital Graubünden, Loëstrasse 170, CH-7000, Chur, Switzerland.
Peter VilligerDepartment of Surgery, Kantonsspital Graubünden, Loëstrasse 170, CH-7000, Chur, Switzerland.
Kantonsspital Graubünden · CHPrivate University in the Principality of Liechtenstein · LI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate morbidity and mortality following complete mesocolic excision (CME) and central vascular ligation (CVL) in patients undergoing right colectomy.

methodsData from consecutive patients undergoing elective right colectomy at a university-affiliated referral centre were retrospectively analysed. Patients who underwent conventional right-sided colonic cancer surgery (January 2001-April 2009, n = 84) were compared to patients who underwent CME/CVL (May 2009-January 2015, n = 71). The primary end point was anastomotic leak. Secondary end points were delayed gastric emptying, severe respiratory failure, mortality and length of hospital stay.

resultsNo significant difference was found in the rate of anastomotic leak (1.2% in the conventional versus 5.6% in the CME/CVL group, p = 0.108). Patients in the CME/CVL group had a higher 90-day mortality rate (7.0% versus 0.0%, p = 0.019). Four out of five deceased patients suffered from aspiration with consecutive respiratory failure. There was a tendency towards delayed gastric emptying in the CME/CVL group (12.7% versus 7.1%, p = 0.246). Clavien-Dindo complication grades ≥ 2 were similar in both groups with 16 (19%) in the conventional and 15 (21.1%) in the CME/CVL group (p = 0.747). CME/CVL patients had a shorter mean length of stay with 11 versus 14 days (p <  0.001).

conclusionsComplete mesocolic excision with central vascular ligation in right colectomy seems to have a higher aspiration rate leading to severe respiratory failure and to higher mortality compared to conventional resection methods. Patient selection for this procedure may therefore be crucial.

Indexed as

AdultAgedAged, 80 and overColectomyColonic NeoplasmsFemaleFollow-Up StudiesHumansLigationMaleMesocolonMiddle AgedMorbidityPostoperative ComplicationsRetrospective StudiesTreatment OutcomeCentral vascular ligationComplete mesocolic excisionMorbidityMortalityRight colectomy

Identifiers

PMID30376849
PMCPMC6208021
OpenAlexW2898908752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.