ArticleBMC pediatrics2018
The clinical respiratory score predicts paediatric critical care disposition in children with respiratory distress presenting to the emergency department.
Article in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Respiratory Severity Scores and High-Flow Nasal Cannula Initiation in Infants With Bronchiolitis: A Multicenter Emergency Department Cohort Study.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Article
- The Clinical Respiratory Score: Diagnostic Performance for Acute Chest Syndrome in Sickle Cell Disease.Pediatric pulmonology · 2026Article
- Etiology-based management spectrum and outcomes of pediatric central airway stenosis: a retrospective cohort study.BMC pulmonary medicine · 2026Article
- Intravenous Terbutaline as Rescue Therapy in Severe Bronchiolitis: A Report of Two Cases.Pakistan journal of medical sciences · 2026Article
- Standardizing HFNC for bronchiolitis: a quality improvement protocol in an Italian children's hospital.European journal of pediatrics · 2026Article
- Pathogen and Patient Characteristics and the Severity of Viral Respiratory Infections in Children.JAMA network open · 2026Article
- Reach, implementation fidelity, and safety of bubble continuous positive airway pressure (bCPAP) therapy in children with severe pneumonia in Pakistan.PLOS global public health · 2026Article
- Implementation of an Institutional Asthma Care Guideline in Hospitalized Children: Effects on Clinical Outcomes and Healthcare Resource Utilization.Journal of asthma and allergy · 2026Article
- Effects of oral rehydration solution-based prophylactic sodium supplementation on clinical outcomes in pediatric pneumonia: A randomized controlled trial.World journal of clinical pediatrics · 2025Article
- Early Prediction of High-flow Nasal Cannula Failure Using Pediatric-modified HACOR Score in Children with Acute Hypoxemic Respiratory Distress: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Status Asthmaticus in the Pediatric ICU: A Comprehensive Review of Management and Challenges.Pediatric reports · 2024Review
- Pediatric emergency department-based asthma education tools and parent/child asthma knowledge.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024Article
- Reduced Serum Brain-Derived Neurotrophic Factor in Infants Affected by Severe Bronchiolitis.Current neuropharmacology · 2024Article
- Article
- [Analysis of ROX Index, ROX-HR Index, and SpOJournal of Korean Academy of Nursing · 2023Article
- Predictors of high-flow nasal cannula failure in pediatric patients with acute respiratory distress.Clinical and experimental pediatrics · 2022Article
- An Italian Multicenter Study on the Epidemiology of Respiratory Syncytial Virus During SARS-CoV-2 Pandemic in Hospitalized Children.Frontiers in pediatrics · 2022Article
- To determine the association between asthma severity and hospital admission measured by Pediatric Respiratory Assessment Measure (PRAM) score at Indus Hospital and Health Network, Karachi, Pakistan, 2020-2021.Pakistan journal of medical sciences · 2022Article
- Vitamin D levels in children with COVID-19: a report from Turkey.Epidemiology and infection · 2021Article
- Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundRespiratory distress is a common presenting complaint in children brought to the Emergency Department (ED). The Clinical Respiratory Score (CRS) has shown promise as a screen for severe illness in High Income Countries. We aimed to validate the admission CRS in children presenting to the ED of a Low-to Middle Income Country.
methodsChildren (1 month to 16 years) presenting with respiratory distress to the ED of the Aga Khan University Hospital, Karachi, Pakistan, between November 2015 to March 2016, were enrolled. The CRS was measured at initial presentation, prior to any management and 2 h after treatment was started. The predictive value for admission to the paediatric critical care units for a variety of cut offs for CRS at presentation were derived.
resultsA total of 112 children (70% male) of median age 12 months (IQR 2, 34.5 months) were enrolled. Patients with severe CRS (score 8-12) at presentation were more likely to be admitted to paediatric critical care (90% vs. 23% with mild-moderate CRS; OR: 5.7; 95% CI: 2.2-15.3, p < 0.001). The sensitivity and specificity of CRS > 3 in predicting outcome were 94% (95% CI 79.8-99.3) and 40% (95% CI 35-45), respectively, with a positive likelihood ratio of 1.6 (95% CI 1.31-1.98) and negative predictive value of 94% (95% CI 81-98).
conclusionAn admission CRS of > 3 in the ED of a Low-to Middle Income Country had excellent predictive value for disease severity, and it should be considered for incorporation into ED triage protocols.
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