Evidence map›Paper›PMID 30376740›Full record

ReviewExpert opinion on emerging drugs2018

An update: emerging drugs to treat squamous cell carcinomas of the head and neck.

Yoon Se Lee, Daniel E Johnson, Jennifer R Grandis

Abstract readReview
In one paragraph

Review in Expert opinion on emerging drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Theranostic Potential ofIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. circFAT1 Promotes Cancer Stemness and Immune Evasion by Promoting STAT3 Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yoon Se Leea Department of Otolaryngology-Head and Neck Surgery , University of California , San Francisco , CA , USA.
Daniel E Johnsona Department of Otolaryngology-Head and Neck Surgery , University of California , San Francisco , CA , USA.
Jennifer R Grandisa Department of Otolaryngology-Head and Neck Surgery , University of California , San Francisco , CA , USA.
University of California, San Francisco · USAsan Medical Center · KR

Funding

WILD TYPE P53-BASED ADJUVANT IMMUNOTHERAPY FOR SCCHNP50CA097190 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 2004 to 2026
$49.6M
Integrating genomics and the protein interactome for HPV+ head and neck cancer therapyR35CA231998 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2018 to 2024
$6.2M
PI3K Pathway Mutations in Head and Neck CancerR01DE023685 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRANDIS, JENNIFER RUBIN, JOHNSON, DANIEL E · 2014 to 2023
$5.1M
STAT-Mediated TGFalpha EGFR Signaling in squamous cell carcinoma of head neckR01CA077308 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRANDIS, JENNIFER RUBIN · 1998 to 2018
$5.0M
GRPR Signaling in SCCHN: Integration with EGFRR01CA098372 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRANDIS, JENNIFER RUBIN · 2004 to 2017
$3.8M
Targeting STAT3 to enhance anti-tumor immunityR01DE028289 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN, JOHNSON, DANIEL E · 2019 to 2023
$3.2M
Implications of Procaspase-8 Mutations in Oral Squamous Cell CarcinomaR01DE024728 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSON, DANIEL E · 2016 to 2020
$2.0M
NCI NIH HHS P50 CA097190NCI NIH HHS R01 CA077308NCI NIH HHS R01 CA098372NCI NIH HHS R35 CA231998NIDCR NIH HHS R01 DE023685NIDCR NIH HHS R01 DE024728NIDCR NIH HHS R01 DE028289
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsErbB ReceptorsHead and Neck NeoplasmsHumansImmunotherapySquamous Cell Carcinoma of Head and NeckAntineoplastic AgentsEGFR protein, humanErbB ReceptorsChemotherapyepidermal growth factor receptorhead and neck squamous cell carcinomaHPVimmunotherapymolecular targeted therapyprogrammed cell death 1 receptorprogrammed cell death ligand 1the Cancer Genome Atlas

Identifiers

PMID30376740
PMCPMC6525082
OpenAlexW2898616908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.