ArticlePloS one2018
Towards fast whole-body PET/MR: Investigation of PET image quality versus reduced PET acquisition times.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- PET/MR Imaging of the Gastrointestinal Tract.Magnetic resonance imaging clinics of North America · 2026Review
- Optimization of PET acquisition time for thoracic lesions inEuropean radiology experimental · 2026Article
- [American journal of nuclear medicine and molecular imaging · 2026Review
- UR-cycleGAN: Denoising full-body low-dose PET images using cycle-consistent Generative Adversarial Networks.Journal of applied clinical medical physics · 2025Article
- Towards a fast PET/MRI protocol for breast cancer imaging: maintaining diagnostic confidence while reducing PET and MRI acquisition times.European radiology · 2023Article
- Validation of Deep Learning-based Augmentation for ReducedRadiology. Artificial intelligence · 2021Article
- The image quality, lesion detectability, and acquisition time ofEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Synthetic CT generation from non-attenuation corrected PET images for whole-body PET imaging.Physics in medicine and biology · 2019Article
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6 authors.
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Abstract
purposeThe trend towards faster acquisition protocols in whole-body positron emission tomography/magnetic resonance (PET/MR) arises the question of whether short PET data acquisition protocols in a whole-body multi-station context allow for reduced PET acquisition times while providing adequate PET image quality and accurate quantification parameters. The study goal is to investigate how reducing PET acquisition times affects PET image quality and quantification in whole-body PET/MR in patients with oncologic findings.
methodsFifty-one patients with different oncologic findings underwent a clinical whole-body 18F-Fluorodeoxyglucose PET/MR examination. PET data was reconstructed with 4, 3, 2, and 1 min/bed time intervals for each patient to simulate the effect of reduced PET acquisition times. The 4-minute PET reconstructions served as reference standard. All whole-body PET data sets were analyzed regarding image quality, lesion detectability, PET quantification and standardized uptake values.
resultsA total of 91 lesions were detected in the 4-minute PET reconstructions. The same number of congruent lesions was also noticed in the 3 and 2 minutes-per-bed (mpb) reconstructed images. A total of 2 lesions in 2 patients was not detected in the 1 minute PET data reconstructions due to poor image quality. Image noise in the blood pool increased from 22.2% (4 mpb) to 42.1% (1 mpb). Signal-to-noise ratio declined with shorter timeframes from 13.1 (4 mpb) to 9.3 (1 mpb). SUVmean and SUVmax showed no significant changes between 4 and 1 mpb reconstructed timeframes.
conclusionsReconstruction of PET data with different time intervals has shown that 2 minutes acquisition time per bed position instead of 4 minutes is sufficient to provide accurate lesion detection and adequate image quality in a clinical setting, despite the trends to lower image quality with shorter PET acquisition times. This provides latitude for potential reduction of PET acquisition times in fast PET/MR whole-body examinations.
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