ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020
Non-invasive optical neuromonitoring of the temperature-dependence of cerebral oxygen metabolism during deep hypothermic cardiopulmonary bypass in neonatal swine.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 45 citations in OpenAlex.
- Article
- Optical and Microdialysis Monitoring of Succinate Prodrug Treatment in a Rotenone-Induced Model of Mitochondrial Dysfunction in Swine.Metabolites · 2026Article
- Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion.Biophotonics discovery · 2025Article
- A novel translational bioinformatics framework for facilitating multimodal data analyses in preclinical models of neurological injury.Scientific reports · 2024Article
- Microvascular reperfusion during endovascular therapy: the balance of supply and demand.Journal of neurointerventional surgery · 2024Article
- Modified Beer-Lambert algorithm to measure pulsatile blood flow, critical closing pressure, and intracranial hypertension.Biomedical optics express · 2024Article
- Evaluation of calibrated and uncalibrated optical imaging approaches for relative cerebral oxygen metabolism measurements in awake mice.Physiological measurement · 2024Article
- Association between ASL MRI-derived cerebral blood flow and outcomes after pediatric cardiac arrest.Resuscitation · 2024Observational
- Chassis-based fiber-coupled optical probe design for reproducible quantitative diffuse optical spectroscopy measurements.PloS one · 2024Article
- Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol.PloS one · 2024Article
- Article
- Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children.Neurocritical care · 2023Review
- Non-invasive diffuse optical monitoring of cerebral physiology in an adult swine-model of impact traumatic brain injury.Biomedical optics express · 2023Article
- Optimizing a two-layer method for hybrid diffuse correlation spectroscopy and frequency-domain diffuse optical spectroscopy cerebral measurements in adults.Neurophotonics · 2023Article
- The intra-arterial selective cooling infusion system: A mathematical temperature analysis and in vitro experiments for acute ischemic stroke therapy.CNS neuroscience & therapeutics · 2022Article
- Proton magnetic resonance spectroscopy assessment of neonatal brain metabolism during cardiopulmonary bypass surgery.NMR in biomedicine · 2022Article
- Low frequency power in cerebral blood flow is a biomarker of neurologic injury in the acute period after cardiac arrest.Resuscitation · 2022Article
- Correlation of Cerebral Microdialysis with Non-Invasive Diffuse Optical Cerebral Hemodynamic Monitoring during Deep Hypothermic Cardiopulmonary Bypass.Metabolites · 2022Article
- Optical imaging and spectroscopy for the study of the human brain: status report.Neurophotonics · 2022Article
- Effects of circulatory arrest and cardiopulmonary bypass on cerebral autoregulation in neonatal swine.Pediatric research · 2022Article
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Authors and funding
22 authors at 5 institutions in 1 country.
Funding
Abstract
Management of deep hypothermic (DH) cardiopulmonary bypass (CPB), a critical neuroprotective strategy, currently relies on non-invasive temperature to guide cerebral metabolic suppression during complex cardiac surgery in neonates. Considerable inter-subject variability in temperature response and residual metabolism may contribute to the persisting risk for postoperative neurological injury. To characterize and mitigate this variability, we assess the sufficiency of conventional nasopharyngeal temperature (NPT) guidance, and in the process, validate combined non-invasive frequency-domain diffuse optical spectroscopy (FD-DOS) and diffuse correlation spectroscopy (DCS) for direct measurement of cerebral metabolic rate of oxygen (
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