ArticleNature communications2018
Helminth-induced IL-4 expands bystander memory CD8
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Effects of schistosomes on host anti-viral immune response and the acquisition, virulence, and prevention of viral infections: A systematic review.PLoS pathogens · 2021Pooled it
- Virtual memory CD8⁺ T cells in aging: heterogeneity, bystander protection, inflammatory potential, and inhibitory regulation.Immunity & ageing : I & A · 2026Review
- Schistosomiasis vaccine SchistoShield® induces functional immune memory responses in US and African populations.NPJ vaccines · 2026Article
- IL-4-STAT6 signaling delays protective CD8Nature immunology · 2026Article
- α-Galactosylceramide-expanded virtual memory CD8Frontiers in immunology · 2026Article
- T cell exhaustion in parasitic infections.Frontiers in immunology · 2026Review
- LCMV-mediated loss of virtual memory CD8 T cells yields a functionally enhanced T cell subset.iScience · 2025Article
- Joining the dots: maternal cytomegalovirus, HIV and the placenta.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Review
- UFL1 promotes survival and function of virtual memory CD8 T cells.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Helminth infections affect host immune responses to viral infections and vaccines.FEMS microbiology reviews · 2025Review
- Bystander CD8Frontiers in immunology · 2025Article
- The intersection of influenza infection and autoimmunity.Frontiers in immunology · 2025Review
- Patients with Trichinella spiralis infection display unmodified antigen-specific immune response to SARS-CoV-2.Memorias do Instituto Oswaldo Cruz · 2025Article
- Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis.The EMBO journal · 2024Article
- Steady-state, therapeutic, and helminth-induced IL-4 compromise protective CD8 T cell bystander activation.bioRxiv : the preprint server for biology · 2024Article
- Systemic Immune Modulation by Gastrointestinal Nematodes.Annual review of immunology · 2024Review
- Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants.Nature communications · 2024Article
- Eosinophils promote CD8Signal transduction and targeted therapy · 2024Article
- The impact of helminth-induced immunity on infection with bacteria or viruses.Veterinary research · 2023Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 5 countries.
Funding
Abstract
Infection with parasitic helminths can imprint the immune system to modulate bystander inflammatory processes. Bystander or virtual memory CD8
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.