Evidence map›Paper›PMID 30375332›Full record

ArticleeLife2018

Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome.

Camilla S Teng, Man-Chun Ting, D'Juan T Farmer, Mia Brockop, Robert E Maxson, J Gage Crump

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  11. Standardization of bone morphometry and mineral density assessments in zebrafish and other small laboratory fishes using X-ray radiography and micro-computed tomography.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Camilla S TengDepartment of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, United States.
Man-Chun TingDepartment of Biochemistry, Keck School of Medicine, University of Southern California, Los Angeles, United States.
D'Juan T FarmerDepartment of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, United States.
Mia BrockopDepartment of Biochemistry, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Robert E MaxsonDepartment of Biochemistry, Keck School of Medicine, University of Southern California, Los Angeles, United States.
J Gage CrumpDepartment of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, United States.ORCID 0000-0002-3209-0026
University of Southern California · US

Funding

Progenitor Regulation in Craniofacial Development and RegenerationR35DE027550 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2017 to 2024
$8.0M
Molecular and Cellular Basis of CraniosynostosisR01DE026339 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2016 to 2025
$6.5M
DOCTORAL AND POST-DOCTORAL TRAINING IN CRANIOFACIAL BIOLOGYT90DE021982 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAINE, MICHAEL LANSDELL · 2011 to 2025
$6.2M
Interactions Between Twist1 and Tcf12 in Craniofacial DevelopmentF31DE024031 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TENG, CAMILLA SUE · 2014 to 2016
$113k
NIDCR NIH HHS F31 DE024031NIDCR NIH HHS F31DE024031NIDCR NIH HHS R01 DE026339NIDCR NIH HHS R01DE026339NIDCR NIH HHS R35 DE027550NIDCR NIH HHS R35DE027550NIDCR NIH HHS T90 DE021982NIDCR NIH HHS T90DE021982
6 · The paper itself

Abstract

Cranial sutures separate the skull bones and house stem cells for bone growth and repair. In Saethre-Chotzen syndrome, mutations in

Indexed as

AcrocephalosyndactyliaAnimalsBasic Helix-Loop-Helix ProteinsBone DevelopmentCraniosynostosesDisease Models, AnimalGene Expression Regulation, DevelopmentalGene Knockout TechniquesHumansMiceMutationNeural CrestOsteogenesisTwist-Related Protein 1ZebrafishBasic Helix-Loop-Helix ProteinsTcf12 protein, mouseTwist-Related Protein 1coronal suturecraniosynostosisdevelopmental biologymouseregenerative medicineSaethre-Chotzen Syndromeskull bonesstem cellsTcf12Twist1zebrafish

Identifiers

PMID30375332
PMCPMC6207424
OpenAlexW2898326636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.