Evidence map›Paper›PMID 30375090›Full record

ArticleJournal of cardiovascular electrophysiology2019

Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging.

Kennosuke Yamashita, Eugene Kholmovski, Elyar Ghafoori, Roya Kamali, Eugene Kwan, Justin Lichter, Robert MacLeod, Derek J Dosdall, Ravi Ranjan

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Effective ablation settings that predict chronic scar after atrial ablation with HELIOSTAR™ multi-electrode radiofrequency balloon catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Ablation-induced left atrial mechanical dysfunction recovers in weeks after ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  7. Review
  8. Article
  9. Ablation Lesion Assessment with MRI.Arrhythmia & electrophysiology review · 2022
    Review
  10. Article
  11. Native contrast visualization and tissue characterization of myocardial radiofrequency ablation and acetic acid chemoablation lesions at 0.55 T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  12. Article
  13. Review
  14. Cryoablation: Another arrow in the Ablationist's Quiver.Indian pacing and electrophysiology journal
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kennosuke YamashitaDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-5630-1975
Eugene KholmovskiDepartment of Radiology and Imaging Sciences, UCAIR, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-3271-7247
Elyar GhafooriDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.
Roya KamaliDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.
Eugene KwanDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.
Justin LichterDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.
Robert MacLeodNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah.
Derek J DosdallDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.
Ravi RanjanDepartment of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-3321-2435
University of Utah · US

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R. · 2012 to 2019
$9.7M
MRI-based visualization and acute targeting of gaps in atrial ablation lesionsK23HL115084 · NHLBI · UNIVERSITY OF UTAH · PI RANJAN, RAVI · 2012 to 2016
$754k
NHLBI NIH HHS K23 HL115084NIGMS NIH HHS P41 GM103545
6 · The paper itself

Abstract

introductionRadiofrequency (RF) and cryoablation are routinely used to treat arrhythmias, but the extent and time course of edema associated with the two different modalities is unknown. Our goal was to follow the lesion maturation and edema formation after RF and cryoablation using serial magnetic resonance imaging (MRI). METHODS AND

resultsVentricular ablation was performed in a canine model (n = 11) using a cryo or an irrigated RF catheter. T2-weighted (T2w) edema imaging and late gadolinium enhancement (LGE)-MRI were done immediately (0 day: acute), 1 to 2 weeks (subacute), and 8 to 12 weeks (chronic) after ablation. After the final MRI, excised hearts underwent pathological evaluation. As a result, 45 ventricular lesions (cryo group: 20; RF group: 25) were evaluated. Acute LGE volume was not significantly different but acute edema volume in cryo group was significantly smaller (1225.0 ± 263.5 vs 1855.2 ± 520.5 mm

conclusionsWhen comparing cryo and RF lesions of similar chronic size, acute edema is larger for RF lesions. Edema resolves in both cryo and RF lesions in 1 to 2 weeks.

Indexed as

Magnetic Resonance ImagingAnimalsContrast MediaCryosurgeryDogsEdema, CardiacHeart VentriclesMeglumineMyocardiumOrganometallic CompoundsPredictive Value of TestsRadiofrequency AblationTime FactorsContrast Mediagadobenic acidMeglumineOrganometallic Compoundscatheter ablationcryoablationlate gadolinium enhancementmagnetic resonance imagingradiofrequency

Identifiers

PMID30375090
PMCPMC6363882
OpenAlexW2899178053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.