ArticleThe European journal of neuroscience2019
Rhythmic auditory cues shape neural network recruitment in Parkinson's disease during repetitive motor behavior.
Article in The European journal of neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Training Involving Rhythmic Auditory Stimulation on Upper-limb Movements in Patients With Parkinson's Disease
Effects and Neural Mechanisms of Training Involving Rhythmic Auditory Stimulation on Upper-limb Movements in Patients With Parkinson's Disease
Effect of Rhythmic Auditory Stimulation (RAS) During Gait on Cortical Activation: A Functional Near-infrared Red Spectroscopy Neuroimaging Study (fNIRS)
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Effectiveness and applications of neurologic music therapy in motor and non-motor rehabilitation for older adults with Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effect of Music Based Therapy Rhythmic Auditory Stimulation (RAS) Using Wearable Device in Rehabilitation of Neurological Patients: A Systematic Review.Sensors (Basel, Switzerland) · 2023Pooled it
- Rhythmic auditory stimulation promotes gait recovery in Parkinson's patients: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Music Therapy and Parkinson's Disease: A Systematic Review from 2015-2020.International journal of environmental research and public health · 2021Pooled it
- Dual-Task-Based Drum Playing with Rhythmic Cueing on Motor and Attention Control in Patients with Parkinson's Disease: A Preliminary Randomized Study.International journal of environmental research and public health · 2021Trial
- Effects of rhythmic auditory cueing on stepping in place in patients with Parkinson's disease.Medicine · 2019Trial
- Walking to your right music: a randomized controlled trial on the novel use of treadmill plus music in Parkinson's disease.Journal of neuroengineering and rehabilitation · 2019Trial
- Auditory cueing modulates motor performance and brain activity in early Parkinson's disease-a kinematic and fMRI study.NPJ Parkinson's disease · 2026Article
- Wakeful targeted memory reactivation during short rest periods modulates early motor learning.NPJ science of learning · 2026Article
- Article
- Discriminative compensatory activation during auditory beat perception in Parkinson's disease and multiple system atrophy.Frontiers in neuroscience · 2026Article
- Evaluation of wrist and finger function in healthy children through music-based video game therapy.Journal of neuroengineering and rehabilitation · 2025Article
- Altered Basal Ganglia Network Topology Associated With Auditory-Motor Synchronization.Brain and behavior · 2025Article
- Effects of auditory rhythmic adaptation on lower limb joint mechanics during single-leg drop landings in individuals with functional ankle instability.Frontiers in human neuroscience · 2025Article
- Personalized auditory cues improve gait in patients with early Parkinson's disease.Frontiers in neurology · 2025Article
- Neural mechanisms underlying synchronization of movement to musical cues in Parkinson disease and aging.Frontiers in neuroscience · 2025Article
- Integration of music-based game approaches with wearable devices for hand neurorehabilitation: a narrative review.Journal of neuroengineering and rehabilitation · 2024Review
- Rhythm and music for promoting sensorimotor organization in autism: broader implications for outcomes.Frontiers in integrative neuroscience · 2024Article
- Article
- Music Therapy for Gait and Speech Deficits in Parkinson's Disease: A Mini-Review.Brain sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
Abstract
It is well established clinically that rhythmic auditory cues can improve gait and other motor behaviors in Parkinson's disease (PD) and other disorders. However, the neural systems underlying this therapeutic effect are largely unknown. To investigate this question we scanned people with PD and age-matched healthy controls using functional magnetic resonance imaging (fMRI). All subjects performed a rhythmic motor behavior (right hand finger tapping) with and without simultaneous auditory rhythmic cues at two different speeds (1 and 4 Hz). We used spatial independent component analysis (ICA) and regression to identify task-related functional connectivity networks and assessed differences between groups in intra- and inter-network connectivity. Overall, the control group showed greater intra-network connectivity in perceptual and motor related networks during motor tapping both with and without rhythmic cues. The PD group showed greater inter-network connectivity between the auditory network and the executive control network, and between the executive control network and the motor/cerebellar network associated with the motor task performance. We interpret our results as indicating that the temporal rhythmic auditory information may assist compensatory mechanisms through network-level effects, reflected in increased interaction between auditory and executive networks that in turn modulate activity in cortico-cerebellar networks.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.