ArticleMagnetic resonance in medicine2019
Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 80 citations in OpenAlex.
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- Clinical Applications of Hyperpolarized Magnetic Resonance Imaging in Brain Tumors: Current Evidence and Future Opportunities.Cancers · 2026Review
- Physiological Interpretation of the Lactate to Pyruvate AUC Ratio for Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Timing Is Everything: How Subtle Timing Changes in MRI Echo Planar Imaging Can Significantly Alter Mechanical Vibrations and Sound Level.Magnetic resonance in medicine · 2026Article
- Evaluation of treatment response in patients with recurrent grade 4 glioma using hyperpolarized [1-Research square · 2026Article
- Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Clinical Translation of HyperpolarizedAJNR. American journal of neuroradiology · 2025Review
- Carbon-13 Hyperpolarization of α-Ketocarboxylates with Parahydrogen in Reversible Exchange.ChemMedChem · 2025Article
- Spatially constrained hyperpolarized 13C MRI pharmacokinetic rate constant map estimation using a digital brain phantom and a U-Net.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025Article
- Hyperpolarized [1-Brain communications · 2025Article
- [Research Progress in Applying HyperpolarizedSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
- Deuterium Metabolic Imaging Differentiates Glioblastoma Metabolic Subtypes and Detects Early Response to Chemoradiotherapy.Cancer research · 2024Article
- Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024Review
- Evidence ofMagnetic resonance in medicine · 2024Article
- HyperpolarizedMagnetic resonance in medicine · 2024Article
- Functional activation of pyruvate dehydrogenase in human brain using hyperpolarized [1-Magnetic resonance in medicine · 2024Article
- Advanced HyperpolarizedCancers · 2024Article
- Imaging cancer metabolism using magnetic resonance.Npj imaging · 2024Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo develop and translate a metabolite-specific imaging sequence using a symmetric echo planar readout for clinical hyperpolarized (HP) Carbon-13 (
methodsInitial data were acquired from patients with prostate cancer (N = 3) and high-grade brain tumors (N = 3) on a 3T scanner. Samples of [1-
resultsHigh pyruvate signal was seen throughout the prostate and brain, with conversion to lactate being shown across studies, whereas bicarbonate production was also detected in the brain. No Nyquist ghost artifacts or obvious geometric distortion from the echo planar readout were observed. The average error in center frequency was 1.2 ± 17.0 and 4.5 ± 1.4 Hz for prostate and brain studies, respectively, below the threshold for spatial shift because of bulk off-resonance.
conclusionThis study demonstrated the feasibility of symmetric EPI to acquire HP
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