Evidence map›Paper›PMID 30374905›Full record

ArticleNatural products and bioprospecting2018

Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.

Yin-E Zhi, Xu-Jie Qi, Hui Liu, Yuan Zeng, Wei Ni, Li He, Zu-Ding Wang, Hai-Yang Liu

Erratum issuedOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Natural products and bioprospecting, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yin-E ZhiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China.
Xu-Jie QiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China.
Hui LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China.
Yuan ZengState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China.
Wei NiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China.
Li HeDepartment of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China.
Zu-Ding WangKunming Botanee Bio-Technique Co. Ltd, Kunming, 650106, China.
Hai-Yang LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, China. haiyangliu@mail.kib.ac.cn.ORCID http://orcid.org/0000-0002-1050-6254
Kunming Institute of Botany · CNKunming Medical University · CN

Funding

National Natural Science Foundation of China 31570363National Natural Science Foundation of China 31770391
6 · The paper itself

Abstract

Phytochemical investigation of the MeOH extract of twigs and leaves of Baeckea frutescens led to the isolation of seven new polymethylated phloroglucinol meroterpenoids (PPMs), named baeckfrutones M-S (1-7). Their structures and absolute configurations were determined by spectroscopic analyses, chiral-phase HPLC analysis, and electronic circular dichroism (ECD) calculations. PPM 1 is a novel meroterpenoid possessing a 6/6/5/3 tetracyclic skeleton in PPMs, whereas 3 and 4 are the first hydroxytasmanone type phloroglucinol-monoterpene hybrids. (+)-2 and 7 displayed potent anti-inflammatory activity with IC

Indexed as

Anti-inflammatory activityBaeckea frutescensMyrtaceaePolymethylated phloroglucinol meroterpenoids

Identifiers

PMID30374905
PMCPMC6224813
OpenAlexW2898762077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.