ArticleSurgical endoscopy2019
EUS-guided irreversible electroporation using endoscopic needle-electrode in porcine pancreas.
Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Review
- A Preliminary Study of a Prototype Cryoablation Needle on Porcine Livers for Pancreatic Cancer Treatment.Journal of clinical medicine · 2024Article
- Nano-Pulse Stimulation Therapy in Oncology.Bioelectricity · 2024Review
- Article
- Endoscopic Ultrasound-Guided Laser Ablation Using a Diffusing Applicator for Locally Advanced Pancreatic Cancer Treatment.Cancers · 2022Article
- An Overview of Cell Membrane Perforation and Resealing Mechanisms for Localized Drug Delivery.Pharmaceutics · 2022Review
- Modeling of a single bipolar electrode with tines for irreversible electroporation delivery.Computers in biology and medicine · 2022Article
- Invasive and non-invasive electrodes for successful drug and gene delivery in electroporation-based treatments.Frontiers in bioengineering and biotechnology · 2022Review
- Evaluation of electroporated area using 2,3,5-triphenyltetrazolium chloride in a potato model.Scientific reports · 2021Article
- Novel Ablation Therapy Using Endoscopic Irreversible Electroporation in the Bile Duct: A Pilot Animal Study.Clinical endoscopy · 2021Article
- Irreversible Electroporation (IRE) in Locally Advanced Pancreatic Cancer: A Review of Current Clinical Outcomes, Mechanism of Action and Opportunities for Synergistic Therapy.Journal of clinical medicine · 2021Review
- [Large Animal Models in Pancreas and Biliary Disease].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- RadioactiveWorld journal of clinical cases · 2021Article
- RadioactiveWorld journal of clinical cases · 2020Article
- Endoscopic Ultrasound-Guided Local Therapy for Pancreatic Neoplasms.Clinical endoscopy · 2020Article
- Electroporation-Based Treatments in Urology.Cancers · 2020Review
- Safety and efficacy of magnetic anchoring electrode-assisted irreversible electroporation for gastric tissue ablation.Surgical endoscopy · 2020Article
- Irreversible Electroporation of the Pancreas.Seminars in interventional radiology · 2019Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic irreversible electroporation (IRE) can be performed using a flexible, thin, needle-shaped electrode for an endoscopic ultrasound (EUS)-guided procedure. This study aimed to evaluate the feasibility and efficacy of performing EUS-guided IRE with endoscopic needle-electrode in porcine pancreas.
methodsExperimental endoscopic IRE on the pancreas were performed by EUS-guided approach in three pigs and compared with surgical approach in three pigs. The animals were killed after 24 h and their pancreases collected.
resultsIRE ablation using endoscopic needle-electrode was successful technically in EUS-guided approaches for the pancreas. Immediately following IRE, the ablated pancreatic tissue showed no gross change except focal hemorrhage. H&E staining presented a well-demarcated ablation site measuring 1.0-1.5 cm in diameter in the pancreas. TUNEL immunohistochemistry showed diffuse cell death along the puncture site 24 h after IRE. No complication was observed in pigs after endoscopic IRE ablation.
conclusionEUS-guided IRE ablation was feasible and effective for pancreas using the newly developed device.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.