Observational studyEuropean journal of pediatrics2019
The superiority of point of care ultrasound in localizing central venous line tip position over time.
Observational study in European journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Prevention of complications related to peripherally inserted central catheter insertion techniques in newborns: systematic review and network meta-analysis.Revista latino-americana de enfermagem · 2024Pooled it
- Adverse events associated with umbilical catheters: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2021Pooled it
- A bibliometric review of peripherally inserted central catheters: Knowledge domain mapping and research trends.Medicine · 2026Review
- Feasibility of neonatal intravenous nutrition for the management of gastroschisis in sub-Saharan Africa.World journal of pediatric surgery · 2026Article
- Neonatal point-of-care ultrasound-guidelines for training, credentialing and quality assurance.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Applications of Point-of-Care-Ultrasound in Neonatology: A Systematic Review of the Literature.Life (Basel, Switzerland) · 2024Review
- Article
- Usefulness of skills in point of care ultrasound and simulation-based training as essential competencies in acute management of neonatal cardiac tamponade.BMJ case reports · 2024Article
- The utility of point-of-care ultrasound protocol to confirm central venous catheter placement in the preterm infant.European journal of pediatrics · 2023Article
- The Role of Ultrasound in Epicutaneo-Caval Catheter Insertion in Neonates: Systematic Review, Meta-Analysis and Future Perspectives.Diagnostics (Basel, Switzerland) · 2023Review
- The advantage of point-of-care ultrasound in central venous catheterization and related pericardial effusion in infants in the NICU.Frontiers in pediatrics · 2023Article
- Point-of-care ultrasound for neonatal central catheter positioning: impact on X-rays and line tip position accuracy.European journal of pediatrics · 2022Article
- Essentials of Neonatal-Perinatal Medicine fellowship: part 2 - clinical education and experience.Journal of perinatology : official journal of the California Perinatal Association · 2022Review
- [A clinical analysis of pericardial effusion caused by central venous catheterization in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- A new technique for difficult removal of a peripherally inserted central venous catheter (PICC) in a neonate.European journal of pediatrics · 2021Article
- Effectiveness of intracavitary electrocardiogram-guided peripherally inserted central catheter tip placement in premature infants: a multicentre pre-post intervention study.European journal of pediatrics · 2020Article
- The authors reply.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019Article
- Improved visualization of peripherally inserted central catheters on chest radiographs of neonates using fractional multiscale image processing.BMC medical imaging · 2019Article
- Comparison of Ultrasound-Guided Umbilical Venous Catheter Insertion with Blind Method: A Randomized Controlled Trial.Biomedicine hubArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The primary objective was to study agreement between X-rays and point of care ultrasound (POC-US) in determining central venous line (CVL) tip position. The secondary objective was to examine malposition rates over time using POC-US. Fifty-six neonates were enrolled who had a CVL placed. Initial X-rays and POC-US were obtained. POC-US was performed daily thereafter for the total of 6 days. US video clips were acquired in four standard echocardiographic views: subcostal, four-chamber, and short- and long-axis parasternal views. Gwet's agreement coefficient (AC1) for agreement measured inter-rater reliability of X-rays and POC-US (correct position/malposition). A generalized linear mixed model for binary clustered data estimated malposition rate over time. All analyses were conducted using SAS version 9.4 and Agree Stat. The study included 108 "pairs" of X-rays and POC-US images. Agreement coefficient (AC1), with respect to correct position/malposition of CVL tip, was high AC1 = 0.872 (UVC-AC1 = 0.814, PICC-AC1 = 0.94). Among birth weight (BW) < 1000 g, 1000-1499 g, and BW > 1500 g, AC1 values were 0.922, 0.774, and 0.873, respectively. CVL tip malposition rate decreased over time.Conclusions: Agreement between POC-US and X-rays for CVL tip position was high, with the highest in BW < 1000 g. The data suggest that POC-US can be used for initial confirmation and follow up of CVL tip position. What is Known • X-ray is currently the gold standard for localizing central venous line (CVL) tip position. • Malposition of CVL tip can lead to life-threatening complications. What is New • POC-US is superior to X-ray as it can follow CVL tip position over time, detecting malpositioned lines, adjusting them in a timely manner thus preventing complications. • Standardizing CVL placement, X-ray acquisition, POC-US acquisition with four views with video clips and ultrasound operator training increases accuracy and thus agreement between X-ray and POC-US. • UVC tip is more likely to be malpositoned than PICC tip. Malposition of UVC tip using POC-US decreased over time due to shrinking of the umbilical cord in the first 48 of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.