Evidence map›Paper›PMID 30374689›Full record

ArticleRheumatology international2019

Common atherosclerosis genetic risk factors and subclinical atherosclerosis in rheumatoid arthritis: the relevance of disease duration.

Bartłomiej Kisiel, Robert Kruszewski, Aleksandra Juszkiewicz, Anna Raczkiewicz, Artur Bachta, Krzysztof Kłos, Krzysztof Duda, Artur Maliborski, Konrad Szymański, Rafał Płoski and 5 more

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In one paragraph

Article in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Bartłomiej KisielDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland. bartlomiejkisiel@wp.pl.ORCID 0000-0001-6311-0475
Robert KruszewskiDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0003-4214-2982
Aleksandra JuszkiewiczDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-2095-2274
Anna RaczkiewiczDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0001-7172-2922
Artur BachtaDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0003-3057-3830
Krzysztof KłosDepartment of Infectious Diseases and Allergology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0001-9629-5680
Krzysztof DudaDepartment of Radiology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-4754-0739
Artur MaliborskiDepartment of Radiology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-7436-9498
Konrad SzymańskiDepartment of Medical Genetics, Medical University of Warsaw, ul. Pawińskiego 3c, 02-106, Warszawa, Poland.ORCID 0000-0003-4297-8034
Rafał PłoskiDepartment of Medical Genetics, Medical University of Warsaw, ul. Pawińskiego 3c, 02-106, Warszawa, Poland.ORCID 0000-0001-6286-5526
Marek SaracynDepartment of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-5800-0500
Stanisław NiemczykDepartment of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0001-8151-860X
Katarzyna KisielDepartment of Pediatric Dermatology, Center of Dermatology, Międzyleski Specialist Hospital, ul. Bursztynowa 2, 04-749, Warszawa, Poland.ORCID 0000-0003-2031-646X
Małgorzata TłustochowiczDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-1535-7227
Witold TłustochowiczDepartment of Internal Diseases and Rheumatology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warszawa, Poland.ORCID 0000-0002-7750-2901
Wojskowy Instytut Medycyny Lotniczej · PLMedical University of Warsaw · PLNational Academy of Medicine · USMiędzyleski Szpital Specjalistyczny w Warszawie · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego N N402 077234
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common systemic autoimmune disease characterized by increased cardiovascular morbidity. Several previous studies assessed associations between common atherosclerotic genetic risk factors and subclinical atherosclerosis (SA) in RA patients, yet most of them gave negative results. We undertook a cross-sectional study to evaluate the association between previously reported SNPs and subclinical atherosclerosis in a cohort of Polish RA patients. 29 SNPs associated with atherosclerosis in general population were genotyped in 289 RA patients: 116 patients with SA (increased carotid intima-media thickness and/or presence of carotid plaque) and 173 patients without SA. To assess the cumulative effect of SNPs we calculated 3 weighted genetic risk scores: GRS

Indexed as

AdultArthritis, RheumatoidAtherosclerosisFemaleGenetic Predisposition to DiseaseHumansLogistic ModelsMaleMiddle AgedPolymorphism, Single NucleotideRisk FactorsTime FactorsAtherosclerosisDisease modifying anti-rheumatic drugsIntima–media thicknessRheumatoid arthritis

Identifiers

PMID30374689
OpenAlexW2899010882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.