ArticleJournal of echocardiography2019
Prognostic value of exercise stress echocardiography in patients with secondary mitral regurgitation: a long-term follow-up study.
Article in Journal of echocardiography, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Systolic Anterior Motion and Dynamic Mitral Regurgitation Following SAVR: A Case of Hemodynamic Optimization Over Intervention.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Moderate ischemic mitral regurgitation at rest is associated with multiple functional vulnerabilities during exercise stress echocardiography.The international journal of cardiovascular imaging · 2026Article
- Unmasking Risk in Mitral Regurgitation: Prognostic Value of Exercise Stress Echocardiography-A Systematic Review.Journal of clinical medicine · 2026Review
- Advancing Cardiovascular Risk Stratification and Functional Assessment: A Narrative Review of CPET and ESE Applications.Healthcare (Basel, Switzerland) · 2025Review
- Papillary Muscle Maneuvers: Pathophysiology-based Approach in Secondary Mitral Regurgitation.Reviews in cardiovascular medicine · 2024Review
- Changes in exercise stress echocardiographic parameters before and after transcatheter mitral valve edge-to-edge repair.Cardiovascular intervention and therapeutics · 2024Article
- Stress echocardiography in valvular heart disease.Frontiers in cardiovascular medicine · 2023Review
- Practical Echocardiographic Approach of the Regurgitant Mitral Valve Assessment.Diagnostics (Basel, Switzerland) · 2022Review
- Dynamic Secondary Mitral Regurgitation: Current Evidence and Challenges for the Future.Frontiers in cardiovascular medicine · 2022Review
- Cardiac Imaging for the Assessment of Left Atrial Mechanics Across Heart Failure Stages.Frontiers in cardiovascular medicine · 2021Review
- Clinical application of stress echocardiography for valvular heart disease.Journal of medical ultrasonics (2001) · 2020Review
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSecondary mitral regurgitation (MR) remains a challenging problem in the diagnosis and treatment of patients with heart failure. Although it is well known that secondary MR is dynamic, the impact of the severity of MR during exercise on long-term outcome has not been fully evaluated. The aim of the present study was to investigate the prognostic value of exercise stress echocardiography (ESE) in patients with secondary MR.
methodsThis prospective study included 118 consecutive patients with secondary MR and left ventricular dysfunction (mean ejection fraction at rest: 38 ± 14%) who underwent semi-supine ESE. Their major cardiovascular events (MACE) including cardiac death were followed up for a median of 41.7 (range: 6-128) months.
resultsMR significantly increased from rest to exercise (effective regurgitant orifice: 0.18 ± 0.09 vs. 0.25 ± 0.12 cm
conclusionsESE provides prognostic information in patients with secondary MR that is useful for predicting long-term outcome.
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Registered trials
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