Evidence map›Paper›PMID 30374625›Full record

ArticleAMB Express2018

Egg yolk immunoglobulin interactions with Porphyromonas gingivalis to impact periodontal inflammation and halitosis.

Wu Qiao, Fang Wang, Xiaochen Xu, Shujun Wang, Joe Mac Regenstein, Bin Bao, Ming Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AMB Express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Volatilomes of Bacterial Infections in Humans.Frontiers in neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Wu QiaoCollege of Food Science and Technology, Shanghai Ocean University, No. 999 Hucheng Ring Road, Pudong New Area, Shanghai, 201306, China.
Fang WangShanghai University of Medicine & Health Sciences, Shanghai, 201318, China.ORCID http://orcid.org/0000-0001-5062-7854
Xiaochen XuShanghai MAXAM Company Limited, Shanghai, 200333, China.
Shujun WangCo-Innovation Center of Jiangsu Marine Bio-industry Technology, Huaihai Institute of Technology, Lianyungang, 222005, China.
Joe Mac RegensteinDepartment of Food Science, Cornell University, Ithaca, NY, 14853-7201, USA.
Bin BaoCollege of Food Science and Technology, Shanghai Ocean University, No. 999 Hucheng Ring Road, Pudong New Area, Shanghai, 201306, China. bbao@shou.edu.cn.
Ming MaCollege of Food Science and Technology, Shanghai Ocean University, No. 999 Hucheng Ring Road, Pudong New Area, Shanghai, 201306, China. mma@shou.edu.cn.
Shanghai Ocean University · CNCornell University · USJiangsu Ocean University · CNMinistry of Agriculture · HUShanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porphyromonas gingivalis is a pathogenic Gram-negative anaerobic bacterium that colonizes the subgingival region of gums. These bacteria can invade periodontal tissues, form plaques, and produce volatile sulfur compounds (VSC) and volatile organic compounds (VOC). Egg yolk immunoglobulin (IgY) that was specifically produced in egg yolks after chickens were challenged with P. gingivalis could control and prevent oral diseases caused by P. gingivalis. The releases of P. gingivalis offensive metabolic odors in vitro and in vivo were determined using a Halimeter and GCMS. With IgY bacterial growth was inhibited, and the relative amounts of VOC and VSC were decreased. The scores for the oral health index and the levels of IL-6 and TNF-α are also decreased. All treatment groups showed significant anti-inflammatory effects, which strongly suggests that specifically IgY against P. gingivalis may be an effective treatment for the prevention and protection of periodontal inflammation and halitosis.

Indexed as

Egg yolk immunoglobulinHalitosisPeriodontal inflammationPorphyromonas gingivalisVolatile organic compoundsVolatile sulfur compounds

Identifiers

PMID30374625
PMCPMC6206315
OpenAlexW2898620478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.