Evidence map›Paper›PMID 30374479›Full record

ArticleNorthern clinics of Istanbul2018

Anti-HDV seroprevalance among patients with previous HBV infection.

Abdurrahman Sahin, Suzan Gurocak, Nurettin Tunc, Ulvi Demirel, Orhan Kursat Poyrazoglu, Handan Akbulut, Mehmet Yalniz, Zulal Asci Toraman, Ibrahim Halil Bahcecioglu

Open access · diamondAbstract read
In one paragraph

Article in Northern clinics of Istanbul, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Abdurrahman SahinDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Suzan GurocakDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Nurettin TuncDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Ulvi DemirelDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Orhan Kursat PoyrazogluDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Handan AkbulutDepartment of Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey.
Mehmet YalnizDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Zulal Asci ToramanDepartment of Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey.
Ibrahim Halil BahceciogluDepartment of Internal Medicine, Faculty of Medicine, Firat University, Division of Gastroenterology, Elazig, Turkey.
Fırat University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis prospective study aimed to determine the prevalence of anti-HDV seropositivity among subjects who had previous hepatitis B virus (HBV) infection.

methodsSubjects who were admitted to the gastroenterology inpatient clinic of our hospital between August 2016 and July 2017 were screened for previous HBV infection. The subjects who had HBV serology compatible with resolved HBV infection were recruited in the study, and the seroprevalance of anti-HDV was studied. Participants answered a short questionnaire regarding their family history of chronic hepatitis B (CHB) and chronic hepatitis D (CHD) infection and risk factors for transmission. Subjects who were anti-HDV positive were recalled for a control visit, and HBV-DNA and HDV-RNA were assayed in the blood samples of the responders.

resultsAmong 554 subjects who had previous HBV infection, 53 (9.6%) were anti-HDV positive. The mean age was 63.1±15.4 years in the anti-HDV-positive group and 65.9±15.6 years in the anti-HDV-negative group (p=0.19). The most common risk factor for both groups was dental procedures (89% vs 80%, p=0.33). Anti-Hbc IgG, anti-Hbs, and anti-HBeAg seropositivity did not differ between the anti-HDV-positive and -negative groups (for all, p>0.05). Although HDV-RNA was not detectable in all studied samples, only one subject had detectable HBV-DNA in the anti-HDV-positive group.

conclusionThis study highlighted the prevalence of anti-HDV among subjects who had resolved HBV infection. Long-term follow-up studies, including after the resolution of both infections, are needed to explore HBV-HDV interactions and the behavioral patterns of these viruses.

Indexed as

Anti-HDVHBV-DNAHDV-RNAprevious HBVtransmission route

Identifiers

PMID30374479
PMCPMC6191552
OpenAlexW2803064851

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.