ArticleJournal of the Endocrine Society2018
Relationship Between Visceral Fat and Plasma Aldosterone Concentration in Patients With Primary Aldosteronism.
Article in Journal of the Endocrine Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Clinical and biochemical outcomes after adrenalectomy for primary aldosteronism in tertiary and quaternary referral centers: data from SOPRANO study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Pooled it
- CT-based body composition enhances prognostic performance of PASO score for surgical outcome in primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The diagnostic role of machine learning models related to visceral fat with sex-specific distribution in subtypes of primary aldosteronism.International journal of medical sciences · 2026Article
- Effects of perirenal fat accumulation on cardiometabolic and renal functions and mineralocorticoid receptor activation in primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Clinical Significance of Skeletal Fat-to-Muscle Ratio in Idiopathic Hyperaldosteronism.Clinical endocrinology · 2025Article
- Glucocorticoids: The culprit behind metabolic disorders in primary Aldosteronism? A narrative review.Journal of clinical & translational endocrinology · 2025Review
- Adipose Composition Before and After Primary Aldosteronism Treatment Depends on Primary Aldosteronism Subtypes and Plasma Aldosterone Concentration Before the Treatment.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Occurrence of Metabolic Disorders in Bilateral Primary Aldosteronism Compared to Unilateral Primary Aldosteronism.Diseases (Basel, Switzerland) · 2025Article
- Recent progress in unraveling cardiovascular complications associated with primary aldosteronism: a succinct review.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Association Between Renal Sinus Fat and Cardiometabolic and Renin-Angiotensin System Parameters in Primary Aldosteronism.Journal of the Endocrine Society · 2023Article
- Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Impact of Primary Aldosteronism in Resistant Hypertension.Current hypertension reports · 2022Review
- Sex-specific Association of Primary Aldosteronism With Visceral Adiposity.Journal of the Endocrine Society · 2022Article
- Association of the ratio of visceral-to-subcutaneous fat volume with renal function among patients with primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- The mineralocorticoid receptor-an emerging player in metabolic syndrome?Journal of human hypertension · 2021Review
- Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism.Frontiers in cardiovascular medicine · 2021Review
- Evaluation of Abdominal Computed Tomography Scans for Differentiating the Discrepancies in Abdominal Adipose Tissue Between Two Major Subtypes of Primary Aldosteronism.Frontiers in endocrinology · 2021Article
- High body fat percentage is associated with primary aldosteronism: a cross-sectional study.BMC endocrine disorders · 2020Article
- Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone-producing adenoma and idiopathic hyperaldosteronism.Journal of diabetes investigation · 2020Article
- Association of visceral adiposity and clinical outcome among patients with aldosterone producing adenoma.BMJ open diabetes research & care · 2020Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextThe involvement of visceral fat in aldosterone secretion has not been reported in patients with primary aldosteronism (PA). Patients with PA are complicated by metabolic syndrome more frequently than those without PA. An excess of visceral fat has been hypothesized to cause an elevation of aldosterone secretion in patients with PA.
objectivesTo clarify the role of visceral fat in the pathophysiology of PA, we investigated the correlation between plasma aldosterone concentration (PAC) and visceral fat parameters in patients with PA.
designThis retrospective observational study comprised 131 patients diagnosed with PA between April 2007 and April 2017 at Sapporo City General Hospital. We divided participants into two PA subtypes, aldosterone-producing adenoma (APA; n = 47) and idiopathic hyperaldosteronism (IHA, n = 84), utilizing adrenal venous sampling. We analyzed the correlations of PAC with visceral fat percentage (VF%), visceral fat area (VFA), and subcutaneous fat area, by evaluating computed tomography studies in each subtype group.
resultsPatients with IHA showed a positive correlation of PAC with VF% (
conclusionsThis study revealed a relationship between visceral adipose tissue and aldosterone production only in patients with IHA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.