Evidence map›Paper›PMID 30374356›Full record

ArticleFrontiers in immunology2018

New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression.

Silvia Pesce, Margherita Squillario, Marco Greppi, Fabrizio Loiacono, Lorenzo Moretta, Alessandro Moretta, Simona Sivori, Patrizio Castagnola, Annalisa Barla, Simona Candiani and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 53 citations in OpenAlex.

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  15. Clinical Impact of KIR2DS3 and KIR2DL3 Genes in Neuroblastoma Patients.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Silvia PesceDepartment of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
Margherita SquillarioDepartment of Informatic Bioengeneering, Robotic and System Engeneering, University of Genoa, Genoa, Italy.
Marco GreppiDepartment of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
Fabrizio LoiaconoImmunology Operative Unit, IRCCS San Martino Polyclinical Hospital, Genoa, Italy.
Lorenzo MorettaDepartment of Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Alessandro MorettaDepartment of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
Simona SivoriDepartment of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
Patrizio CastagnolaDepartment of Integrated Oncological Therapies, IRCCS San Martino Polyclinical Hospital, Genoa, Italy.
Annalisa BarlaDepartment of Informatic Bioengeneering, Robotic and System Engeneering, University of Genoa, Genoa, Italy.
Simona CandianiDepartment of Earth Science, Environment and Life (DISTAV), University of Genoa, Genoa, Italy.
Emanuela MarcenaroDepartment of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
University of Genoa · ITOspedale Policlinico San Martino · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer cells are cytotoxic innate lymphoid cells that play an important role for early host defenses against infectious pathogens and surveillance against tumor. In humans, NK cells may be divided in various subsets on the basis of the relative CD56 expression and of the low-affinity FcγRIIIA CD16. In particular, the two main NK cell subsets are represented by the CD56

Indexed as

TranscriptomeBiomarkersCell DifferentiationComputational BiologyGene Expression ProfilingGene Expression RegulationHumansKiller Cells, NaturalLymphocyte SubsetsMicroRNAsReceptors, KIRReproducibility of ResultsBiomarkersMicroRNAsMIRN146 microRNA, humanReceptors, KIRCD56brightCD56dimKIRmiRNAmiRNA microarraysmultivariate statistical analysisNK cellsNK cell subsets

Identifiers

PMID30374356
PMCPMC6196268
OpenAlexW2897317759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.