Evidence map›Paper›PMID 30374222›Full record

ArticlePaediatrics & child health2018

Screening for kidney disease in Indigenous Canadian children: The FINISHED screen, triage and treat program.

Allison Dart, Barry Lavallee, Caroline Chartrand, Lorraine McLeod, Thomas W Ferguson, Navdeep Tangri, Audrey Gordon, Tom Blydt-Hansen, Claudio Rigatto, Paul Komenda

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Paediatrics & child health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03595267 (Optimal Approaches to Chronic Kidney Disease Case Finding in Indigenous Communities), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03595267 recruitingnot on this mapstarted 2019, after this paper: background citation

Optimal Approaches to Chronic Kidney Disease Case Finding in Indigenous Communities

TypeobservationalSponsorUniversity of ManitobaRan2019 to 2025Enrolled2,500ConditionsChronic Kidney Disease, Diabetes, HypertensionArmsPoint-of-care screening
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The impact of rural status on pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  8. Review
  9. Review
  10. Impact of a screen, triage and treat program for identifying chronic disease risk in Indigenous children.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Observational
  11. Article
  12. Article
  13. Intrauterine exposure to diabetes and risk of cardiovascular disease in adolescence and early adulthood: a population-based birth cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Allison DartDepartment of Pediatrics and Child Health, University of Manitoba and Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
Barry LavalleeCentre for Aboriginal Health Education, University of Manitoba, Winnipeg, Manitoba, Canada.
Caroline ChartrandDiabetes Integration Project, Winnipeg, Manitoba, Canada.
Lorraine McLeodDiabetes Integration Project, Winnipeg, Manitoba, Canada.
Thomas W FergusonDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Navdeep TangriDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Audrey GordonWinnipeg Regional Health Authority, Winnipeg, Manitoba, Canada.
Tom Blydt-HansenUniversity of British Columbia, Vancouver, British Columbia, Canada.
Claudio RigattoDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Paul KomendaDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CADiabetes Canada · CAUniversity of British Columbia · CAWinnipeg Regional Health Authority · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndigenous populations are disproportionately affected by kidney failure at younger ages than other ethnic groups in Canada. As symptoms do not occur until disease is advanced, early kidney disease risk is often unrecognized.

objectivesWe sought to evaluate the yield of community-based screening for early risk factors for kidney disease in youth from rural Indigenous communities in Canada.

methodsThe FINISHED project screened 11 rural First Nations communities in Manitoba, Canada after community and school engagement. The results for the 10- to 17-year olds are reported here. Body mass index (BMI), blood pressure, estimated glomerular filtration rate (eGFR), hemoglobin A1c's (HbA1c) and urine albumin-to-creatinine ratios (ACR) were assessed. All children were triaged and referred to either primary or tertiary care, depending on risk.

resultsA total of 353 were screened (estimated 22.4% of population). The median age was 12 years (IQR 10 to 13), 55% were female and 55% were overweight or obese. Overall, 21.8% of children had at least one abnormality. Hypertension was identified in 5.4% and 11.9% had prehypertension. None of the children had an eGFR < 60 ml/min/1.73 m

conclusionsRisk factors for chronic kidney disease are highly prevalent in rural Indigenous children. More research is required to confirm the persistence of these findings, and to evaluate the efficacy of screening children to prevent or delay progression to kidney failure.

Indexed as

DiabetesHypertensionKidney diseasePaediatricScreening

Identifiers

PMID30374222
PMCPMC6199631
OpenAlexW2797783978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.