Evidence map›Paper›PMID 30374169›Full record

ArticleNature microbiology2018

Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2.

Roenick P Olmo, Alvaro G A Ferreira, Tatiane C Izidoro-Toledo, Eric R G R Aguiar, Isaque J S de Faria, Kátia P R de Souza, Kátia P Osório, Lauriane Kuhn, Philippe Hammann, Elisa G de Andrade and 12 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 83 citations in OpenAlex.

  1. Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Infectivity and Dissemination of Dengue Virus-1 in DifferentTropical medicine and infectious disease · 2025
    Article
  8. Viruses · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Challenges of Robust RNAi-Mediated Gene Silencing inInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. High capacity of BrazilianbioRxiv : the preprint server for biology · 2023
    Article
  19. Review
  20. RNA interference is essential to modulating the pathogenesis of mosquito-borne viruses in the yellow fever mosquitoProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 2 countries.

Roenick P OlmoDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.ORCID http://orcid.org/0000-0002-3849-8591
Alvaro G A FerreiraDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Tatiane C Izidoro-ToledoDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Eric R G R AguiarDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Isaque J S de FariaDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Kátia P R de SouzaDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Kátia P OsórioDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Lauriane KuhnPlateforme Protéomique Strasbourg-Esplanade FRC 1589, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Philippe HammannPlateforme Protéomique Strasbourg-Esplanade FRC 1589, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Elisa G de AndradeDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Yaovi Mathias TodjroDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Marcele N RochaMosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto de Pesquisas René Rachou - Fiocruz, Belo Horizonte/MG, Brazil.
Thiago H J F LeiteDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Siad C G AmadouDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Juliana N ArmacheDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil.
Simona ParoUniversité de Strasbourg, CNRS UPR9022, Inserm U1257, Strasbourg, France.
Caroline D de OliveiraMosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto de Pesquisas René Rachou - Fiocruz, Belo Horizonte/MG, Brazil.
Fabiano D CarvalhoMosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto de Pesquisas René Rachou - Fiocruz, Belo Horizonte/MG, Brazil.
Luciano A MoreiraMosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto de Pesquisas René Rachou - Fiocruz, Belo Horizonte/MG, Brazil.
Eric MaroisUniversité de Strasbourg, CNRS UPR9022, Inserm U1257, Strasbourg, France.
Jean-Luc ImlerUniversité de Strasbourg, CNRS UPR9022, Inserm U1257, Strasbourg, France.
João T MarquesDepartment of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte/MG, Brazil. jtm@ufmg.br.ORCID http://orcid.org/0000-0002-3457-3320
Universidade Federal de Minas Gerais · BRInstituto de Ensino e Pesquisa Santa Casa · BRCentre National de la Recherche Scientifique · FRInstitut de Biologie Moléculaire et Cellulaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV) is an arbovirus transmitted to humans by Aedes mosquitoes

Indexed as

Ectopic Gene ExpressionAedesAnimalsAnimals, Genetically ModifiedAntiviral AgentsCarrier ProteinsDengueDengue VirusDNA ReplicationDrosophila ProteinsFemaleGastrointestinal TractGene SilencingHost-Pathogen InteractionsMosquito VectorsRNA-Binding ProteinsAntiviral AgentsCarrier ProteinsDrosophila ProteinsLoqs protein, DrosophilaRNA-Binding ProteinsRNA, Double-StrandedRNA, Small InterferingRNA, Viral

Identifiers

PMID30374169
OpenAlexW2896675470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.