ArticlePediatric research2019
Oxygen desaturations in the early neonatal period predict development of bronchopulmonary dysplasia.
Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 74 citations in OpenAlex.
- Clinician Perspectives of Oxygen Control in Children With Bronchopulmonary Dysplasia at Home: An International Survey of Clinicians From 44 Countries.Journal of paediatrics and child health · 2026Article
- Prediction of bronchopulmonary dysplasia seven days after birth using respiratory and oxygenation timeseries with machine learning.Pediatric research · 2026Article
- Car seat tolerance screen failure in the neonatal intensive care unit: clinical, oxygen saturation and heart rate analysis.Pediatric research · 2026Article
- Endotracheal tube exchange in preterm infants with evolving chronic lung disease: safety, outcomes, and impacts on pulmonary mechanics.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Oxidant Stress, Hyperoxia/Hypoxia and Neonatal Respiratory Disorders.Antioxidants (Basel, Switzerland) · 2025Review
- The Clinical Relevance of Overnight Oximetry in the Diagnosis of Intermittent Desaturations and the Need for Home Oxygen in the Near-Term and Term Infant.Children (Basel, Switzerland) · 2025Review
- Oxygenation Instability and Short-Term Morbidities Among Very-Low-Birthweight Premature Infants.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Neonatal intermittent hypoxemia events are associated with later systemic hypertension.Pediatric research · 2025Article
- Construction and Validation of a Risk Prediction Model for Early Severe Intraventricular Hemorrhage in Very Low Birth Weight Infants.The Kaohsiung journal of medical sciences · 2025Article
- Impact of Pharmacologic Patent Ductus Arteriosus Treatment on Acute Respiratory and Oxygenation Metrics in Very Low Birth Weight Infants.American journal of perinatology · 2025Article
- Tachycardia-Desaturation Episodes in Neonatal Intensive Care Unit Patients with and without Bronchopulmonary Dysplasia.American journal of perinatology · 2025Article
- Energy Utilization in Premature Neonates Undergoing Screening for Retinopathy of Prematurity.Pediatric reports · 2025Article
- Intermittent Hypoxemia and Neurodevelopmental Impairment at 12 and 24 Months in Preterm Infants.Neonatology · 2025Article
- Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Infants Born Extremely Preterm.The Journal of pediatrics · 2024Observational
- Heart Rate and Pulse Oximetry Dynamics in the First Week after Birth in Neonatal Intensive Care Unit Patients and the Risk of Cerebral Palsy.American journal of perinatology · 2024Article
- Maturation of cardioventilatory physiological trajectories in extremely preterm infants.Pediatric research · 2024Article
- Article
- Transforming neonatal care with artificial intelligence: challenges, ethical consideration, and opportunities.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Prediction of bronchopulmonary dysplasia in very preterm infants: competitive risk model nomogram.Frontiers in pediatrics · 2024Article
- Plasma serotonergic biomarkers are associated with hypoxemia events in preterm neonates.Pediatric research · 2023Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundBradycardia and oxygen desaturation episodes are common among preterm very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU), and their association with adverse outcomes such as bronchopulmonary dysplasia (BPD) is unclear.
methodsFor 502 VLBW infants we quantified bradycardias (HR < 100 for ≥ 4 s) and desaturations (SpO
resultsBPD occurred in 187 infants (37%). The clinical risk model had ROC area for BPD of 0.874. Measures of desaturation, but not bradycardia, significantly added to the predictive model. Desaturation metrics also added to clinical risks for prediction of severe intraventricular hemorrhage, retinopathy of prematurity and prolonged length of stay in the NICU.
conclusionsOxygen desaturations in the first month of the NICU course are associated with risk of BPD and other morbidities in VLBW infants.
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Registered trials
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