Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors at 4 institutions in 1 country.
Hairui SuDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.
Chiao-Wang SunDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.
Szu-Mam LiuDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.
Xin HeDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute of City of Hope, Duarte, CA.
Hao HuDepartment of Pharmaceutical & Biomedical Sciences, The University of Georgia, Athens, GA.
Kevin M PawlikDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.
Tim M TownesDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.
Xiaosi HanDepartment of Neurology and.
Christopher A KlugDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL.
Maged HenaryDepartment of Chemistry, Georgia State University, Atlanta, GA; and.
Yabing ChenDepartment of Pathology and Birmingham VA Medical Center, The University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0001-9676-6657
Ling LiDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute of City of Hope, Duarte, CA.
Y George ZhengDepartment of Pharmaceutical & Biomedical Sciences, The University of Georgia, Athens, GA.ORCID 0000-0001-7116-3067
Xinyang ZhaoDepartment of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0001-6677-7072
University of Alabama at Birmingham · USCity of Hope · USUniversity of Georgia · USGeorgia State University · US
Funding
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
ROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5M
Molecular Signaling in Oxidative Stress-induced Vascular CalcificationR01HL092215 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHEN, YABING · 2009 to 2018
$3.6M
Regulation of vascular smooth muscle cell function in atherosclerosisR01HL136165 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHEN, YABING · 2017 to 2020
$2.1M
Targeting PRMT5 in Cancer Initiating Cells as a New Therapy for GlioblastomaR01NS095626 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HAN, XIAOSI · 2015 to 2019
$1.6M
O-GlcNAcylation regulates vascular smooth muscle cells in diabetic vasculopathyR01DK100847 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHEN, YABING · 2014 to 2017
$1.3M
Mechanism and Inhibition of Protein Arginine MethylationR01GM126154 · NIGMS · UNIVERSITY OF GEORGIA · PI ZHENG, Y. GEORGE · 2018 to 2021
$1.2M
The Functions of antisense RNA AS-RBM15 in hematopoiesisR01DK110574 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHAO, XINYANG · 2017 to 2019
$668k
PRMT1-mediated metabolic reprogramming in leukemia progressionR21CA202390 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KLUG, CHRISTOPHER, ZHAO, XINYANG · 2016 to 2017
$352k
BLR&D Research Career Scientist Award ApplicationIK6BX003617 · VA · BIRMINGHAM VA MEDICAL CENTER · PI CHEN, YABING · 2017 to 2021
–
Toll-like receptor signaling in pathogenesis of pulmonary hypertensionI01BX000369 · VA · BIRMINGHAM VA MEDICAL CENTER · PI CHEN, YABING · 2009 to 2013
Dynamic regulation of histone modification enzymes such as PRMT1 (protein arginine methyltransferase 1) determines the ordered epigenetic transitions in hematopoiesis. Sorting cells according to the expression levels of histone modification enzymes may further define subpopulations in hematopoietic lineages with unique differentiation potentials that are presently defined by surface markers. We discovered a vital near infrared dye, E84, that fluoresces brightly following binding to PRMT1 and excitation with a red laser. The staining intensity as measured by flow cytometry is correlated with the PRMT1 expression level. Importantly, E84 staining has no apparent negative effect on the proliferation of the labeled cells. Given that long-term hematopoietic stem cells (LT-HSCs) produce low levels of PRMT1, we used E84 to sort LT-HSCs from mouse bone marrow. We found that SLAM (the signalling lymphocyte activation molecule family) marker-positive LT-HSCs were enriched in the E84
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Defining the epigenetic status of blood cells using a cyanine-based fluorescent probe for PRMT1. · full record | OpenQuestion