Evidence map›Paper›PMID 30373854›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Thymic Epithelial Cell Support of Thymopoiesis Does Not Require

Yan Xing, Michelle J Smith, Christine A Goetz, Ron T McElmurry, Sarah L Parker, Dullei Min, Georg A Hollander, Kenneth I Weinberg, Jakub Tolar, Heather E Stefanski and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Yan XingDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0003-2150-1448
Michelle J SmithDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.
Christine A GoetzDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.
Ron T McElmurryDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.
Sarah L ParkerDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.
Dullei MinDivision of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford Medicine, Stanford University, Palo Alto, CA 94304.
Georg A HollanderDepartment of Biomedicine, University of Basel, 4056 Basel, Switzerland; and.ORCID 0000-0002-8790-0874
Kenneth I WeinbergDivision of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford Medicine, Stanford University, Palo Alto, CA 94304.
Jakub TolarDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-0957-4380
Heather E StefanskiDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0001-7527-9315
Bruce R BlazarDivision of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455; blaza001@umn.edu.ORCID 0000-0002-9608-9841
University of Minnesota · USStanford Medicine · USUniversity of Basel · CH

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
COMPUTERIZED SYMPTOM REPORT CONSULT FOR CANCER PATIENTSR01CA081918 · NCI · UNIVERSITY OF WASHINGTON · PI WILKIE, DIANA J · 1999 to 2006
$3.9M
NCI NIH HHS P01 CA065493NCI NIH HHS P30 CA077598
6 · The paper itself

Abstract

Age-related thymic involution is characterized by a decrease in thymic epithelial cell (TEC) number and function parallel to a disruption in their spatial organization, resulting in defective thymocyte development and proliferation as well as peripheral T cell dysfunction. Deficiency of

Indexed as

Adoptive TransferAgingAging, PrematureAnimalsCells, CulturedDiet TherapyEpithelial CellsFibroblast Growth FactorsGlucuronidaseKlotho ProteinsMiceMice, Inbred C57BLMice, KnockoutThymocytesThymus GlandT-LymphocytesFibroblast Growth FactorsGlucuronidaseKlotho ProteinsVitamin D

Identifiers

PMID30373854
PMCPMC6275142
OpenAlexW2898742135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.