Evidence map›Paper›PMID 30373785›Full record

ArticleBMJ open2018

Use of an electronic patient-reported outcome measure in the management of patients with advanced chronic kidney disease: the RePROM pilot trial protocol.

Derek Kyte, Jon Bishop, Elizabeth Brettell, Melanie Calvert, Paul Cockwell, Mary Dutton, Helen Eddington, Gabby Hadley, Natalie J Ives, Louise J Jackson and 2 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Review
  7. Article
  8. Review
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  11. Article
  12. Key methodological considerations for usability testing of electronic patient-reported outcome (ePRO) systems.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Derek KyteCentre for Patient-Reported Outcomes Research, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Jon BishopBirmingham Clinical Trials Unit (BCTU), Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Elizabeth BrettellBirmingham Clinical Trials Unit (BCTU), Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Melanie CalvertCentre for Patient-Reported Outcomes Research, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-1856-837X
Paul CockwellDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Mary DuttonDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Helen EddingtonDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Gabby HadleyDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Natalie J IvesBirmingham Clinical Trials Unit (BCTU), Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Louise J JacksonHealth Economics Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Stephanie StringerDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Marie ValenteBirmingham Clinical Trials Unit (BCTU), Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
University of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

Department of Health PDF-2016-09-009
6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) affects up to 16% of adults in the UK. Patient quality of life is particularly reduced in end-stage renal disease and is strongly associated with increased hospitalisation and mortality. Thus, accurate and responsive healthcare is a key priority. Electronic patient-reported outcome measures (ePROMs) are online questionnaires which ask patients to self-rate their health status. Evidence in oncology suggests that the use of ePROM data within routine care, alongside clinical information, may enhance symptom management and improve patient outcomes. However, National Health Service (NHS)-based ePROM research in CKD is lacking. This pilot trial will assess the feasibility of undertaking a full-scale randomised controlled trial (RCT) in patients with CKD within the NHS. METHODS AND ANALYSIS: The renal ePROM pilot trial is an investigator-led single-centre, open-label, two-arm randomised controlled pilot trial of 66 participants ≥18 years with advanced CKD. Participants will be randomised to receive either usual care or usual care supplemented with an ePROM intervention. Participants within the intervention arm will be asked to submit monthly self-reports of their health status using the ePROM system. The system will provide tailored information to patients in response to each report and notify the clinical team of patient deterioration. The renal clinical team will monitor for ePROM notifications and will respond with appropriate action, in line with standard clinical practice. Measures of study feasibility, participant quality of life and CKD severity will be completed at 3 monthly intervals. Health economic outcomes will be assessed. Clinicians will record treatment decision-making. Acceptability and feasibility of the protocol will be assessed alongside outcome measure and intervention compliance rates. Qualitative process evaluation will be conducted. ETHICS AND DISSEMINATION: The findings will inform the design of a full-scale RCT and the results will be submitted for publication in peer-reviewed journals. The study has ethical approval. TRIAL REGISTRATION NUMBERS: ISRCTN12669006; Pre-results.

Indexed as

Patient Reported Outcome MeasuresQuality of LifeFeasibility StudiesHumansOutcome and Process Assessment, Health CarePilot ProjectsRandomized Controlled Trials as TopicRenal Insufficiency, Chronicchronic renal failureend stage renal failurepatient-reported outcomessymptom monitoring

Identifiers

PMID30373785
PMCPMC6224762
OpenAlexW2899108416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.