Evidence map›Paper›PMID 30373774›Full record

ArticleThe Journal of biological chemistry2018

A nucleosome-free region locally abrogates histone H1-dependent restriction of linker DNA accessibility in chromatin.

Laxmi Narayan Mishra, Jeffrey J Hayes

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Beyond the mono-nucleosome.Biochemical Society transactions · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The solid and liquid states of chromatin.Epigenetics & chromatin · 2021
    Review
  11. Article
  12. Article
  13. Mechanistic insights into KDM4A driven genomic instability.Biochemical Society transactions · 2021
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laxmi Narayan MishraFrom the Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642.
Jeffrey J HayesFrom the Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642 Jeffrey_Hayes@urmc.rochester.edu.ORCID 0000-0001-6981-1803
University of Rochester Medical Center · US

Funding

Histone Tall Interactions and Functions in ChromatinR01GM052426 · NIGMS · UNIVERSITY OF ROCHESTER · PI HAYES, JEFFREY J · 1995 to 2021
$6.2M
NIGMS NIH HHS R01 GM052426
6 · The paper itself

Abstract

Eukaryotic genomes are packaged into linker-oligonucleosome assemblies, providing compaction of genomic DNA and contributing to gene regulation and genome integrity. To define minimal requirements for initial steps in the transition of compact, closed chromatin to a transcriptionally active, open state, we developed a model

Indexed as

AcetylationAnimalsChromatinChromatin Assembly and DisassemblyDNAHistonesNucleosomesXenopus laevisChromatinDNAHistonesNucleosomeschromatinchromatin regulationchromatin structureepigeneticsgene regulationhistonehistone acetylationhistone H1linker histonenucleosomenucleosome free region

Identifiers

PMID30373774
PMCPMC6302178
OpenAlexW2898944808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.