Evidence map›Paper›PMID 30373694›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Risk of Cardiovascular Disease Related to Smoking Is Greater Among Women With Sleep-Disordered Breathing.

Lucas M Donovan, Laura C Feemster, Martha E Billings, Laura J Spece, Matthew F Griffith, Peter J Rise, Elizabeth C Parsons, Brian N Palen, Daniel J O'Hearn, Susan Redline and 2 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lucas M DonovanVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Laura C FeemsterVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Martha E BillingsDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, Washington.
Laura J SpeceVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Matthew F GriffithVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Peter J RiseVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Elizabeth C ParsonsVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Brian N PalenVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Daniel J O'HearnVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Susan RedlineDivision of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
David H AuVeterans Affairs Puget Sound Healthcare System, Seattle, Washington.
Vishesh K KapurDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, Washington.
VA Puget Sound Health Care System · USUniversity of Washington · USBrigham and Women's Hospital · US

Funding

RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
National Sleep Research Resource (NSRR)R24HL114473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S., ZHANG, GUO-QIANG · 2013 to 2017
$7.5M
Facilitating adoption of COPD evidence-based care in outpatient settings (FACES)K23HL111116 · NHLBI · UNIVERSITY OF WASHINGTON · PI FEEMSTER, LAURA CECERE · 2013 to 2017
$481k
Predictors, consequences, and motivations of benzodiazepine use in patients with chronic obstructive pulmonary diseaseF32HL140685 · NHLBI · UNIVERSITY OF WASHINGTON · PI DONOVAN, LUCAS MATTHEW · 2018 to 2018
$55k
NHLBI NIH HHS F32 HL140685NHLBI NIH HHS K23 HL111116NHLBI NIH HHS R24 HL114473NHLBI NIH HHS T32 HL007287
6 · The paper itself

Abstract

STUDY

objectivesAlthough both sleep-disordered breathing (SDB) and smoking are associated with cardiovascular disease (CVD), the potential for an interactive effect on CVD risk has not been explored. Our objective was to determine if smoking-related risk for CVD rises with greater SDB severity.

methodsPolysomnography and smoking history were obtained in 3,852 men and women in the Sleep Heart Health Study without baseline CVD. Fine-Gray proportional hazard models accounting for competing risk were used to calculate risk of incident CVD associated with SDB severity (defined by clinical cutoffs of the apnea-hypopnea index), smoking status (never, former, and current) and their interaction adjusting for potential confounders.

resultsOver a mean (standard deviation) follow-up period of 10.3 (3.4) years, there were 694 incident CVD events. We found a significant three-way interaction of sex, current smoking, and moderate to severe SDB (

conclusionsIn women, smoking-related risk for CVD is significantly higher among individuals with moderate to severe SDB.

Indexed as

AgedCardiovascular DiseasesCohort StudiesCorrelation of DataFemaleHumansMaleMiddle AgedPolysomnographyProspective StudiesRiskSex FactorsSleep Apnea, ObstructiveSmokingcardiovascular diseasesleep-disordered breathingsmoking

Identifiers

PMID30373694
PMCPMC6223561
OpenAlexW2901047549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.