Evidence map›Paper›PMID 30373672›Full record

ArticleActa neuropathologica communications2018

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [

Shannon L Risacher, Martin R Farlow, Daniel R Bateman, Francine Epperson, Eileen F Tallman, Rose Richardson, Jill R Murrell, Frederick W Unverzagt, Liana G Apostolova, Jose M Bonnin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Acta neuropathologica communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  7. Tau filaments with the Alzheimer fold in cases withbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shannon L RisacherDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA. srisache@iupui.edu.
Martin R FarlowIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Daniel R BatemanIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Francine EppersonIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Eileen F TallmanDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.
Rose RichardsonIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Jill R MurrellIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Frederick W UnverzagtIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Liana G ApostolovaDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.
Jose M BonninDepartment of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Bernardino GhettiIndiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA. bghetti@iupui.edu.
Andrew J SaykinDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA. asaykin@iu.edu.
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · US

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GHETTI, BERNARDINO FRANCESCO · 1991 to 2020
$37.3M
Memory Circuitry in MCI and Early Alzheimer’s Disease Prodrome: Molecular DriversR01AG019771 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 2001 to 2021
$6.9M
Sensory and Perceptual Measures as Biomarkers of Alzheimer's Disease PathologyK01AG049050 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI RISACHER, SHANNON L · 2015 to 2019
$612k
NIA NIH HHS K01 AG049050NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG019771
6 · The paper itself

Abstract

This study aimed to determine the pattern of [

Indexed as

Positron-Emission TomographyAgedAlzheimer DiseaseBrainCarbolinesDNA-Binding ProteinsFemaleGerstmann-Straussler-Scheinker DiseaseHumansInfantMagnetic Resonance ImagingMaleMiddle AgedMutationPrion Proteinstau Proteins7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinesDNA-Binding ProteinsPrion ProteinsPRNP protein, humanTARDBP protein, humantau Proteins[18F]flortaucipir/AV-1451/T-807Gerstmann-Sträussler-Scheinker disease (GSS)Positron emission tomography (PET)Prion protein (PrP)PRNP F198S mutationTau

Identifiers

PMID30373672
PMCPMC6205777
OpenAlexW2899081475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.