ArticleBMC cancer2018
Colon cancer patients with a serious psychiatric disorder present with a more advanced cancer stage and receive less adjuvant chemotherapy - A Nationwide Danish Cohort Study.
Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Colorectal cancer treatment in people with severe mental illness: a systematic review and meta-analysis.Epidemiology and psychiatric sciences · 2022Pooled it
- Impact of Schizophrenia Spectrum Disorders on the Receipt of Invasive and Systemic Therapy for Colorectal Cancer: A Nationwide Multicenter Retrospective Cohort Study in Japan.Acta psychiatrica Scandinavica · 2026Article
- Anxiety and depression in non-cardiac surgical patients and associations with adverse outcomes: A systematic review and meta-analysis.Journal of anesthesia and translational medicine · 2025Review
- Stage at diagnosis and breast cancer-specific mortality in breast cancer patients treated with antidepressants, anxiolytics, and antipsychotics: a population-based cohort study from Northern Ireland.Breast cancer research and treatment · 2025Article
- Inclusion in the cancer patient pathway among cancer patients with and without pre-existing mental or substance use disorders: a nationwide register-based study.BMC public health · 2025Article
- Mental illness and non-metastatic colorectal cancer treatment and survival, a nationwide study of almost 70,000 patients.Acta oncologica (Stockholm, Sweden) · 2025Article
- Inequities in the Time to Colon Cancer Diagnosis Among Individuals With Severe Psychiatric Illness.Cancer medicine · 2025Article
- Changes in Psychological Condition during Cancer Chemotherapy.Asian Pacific journal of cancer prevention : APJCP · 2024Observational
- Experiences of Everyday Life among Individuals with Co-Existence of Serious Mental Illness and Cancer-A Qualitative Systematic Literature Review.Healthcare (Basel, Switzerland) · 2023Review
- Risk and mortality of testicular cancer in patients with neurodevelopmental or other psychiatric disorders.British journal of cancer · 2023Article
- The impact of schizophrenia spectrum disorder, bipolar disorder and borderline personality disorder on radiotherapy treatment and overall survival in cancer patients: A matched pair analysis.Clinical and translational radiation oncology · 2023Article
- Analysis of the survival and clinical characteristics of colorectal cancer patients with mental disorders.Annals of gastroenterological surgery · 2021Article
- The clinical and financial cost of mental disorders among elderly patients with gastrointestinal malignancies.Cancer medicine · 2020Article
- Impact of the COVID-19 outbreak on adjuvant chemotherapy for patients with stage II or III colon cancer: experiences from a multicentre clinical trial in China.Current oncology (Toronto, Ont.) · 2020Article
- Improving management of comorbidity in patients with colorectal cancer using comprehensive medical assessment: a pilot study.BMC cancer · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPsychiatric patients with colorectal cancer may have delayed diagnosis and be oncologically undertreated.
methodsThe Danish Colorectal Cancer Group database comprised 25,194 colorectal cancer patients (CRC), (colon cancer (CC, n = 16,641), rectal cancer (RC, n = 8553)), having an operation in 2007-2013, were alive at least 30 days after operation, of which 422 have had at least one hospital contact for a serious psychiatric disorder; ICD-10: DF20-29: primary psychotic disorders, or DF30-39: affective disorders (exposed) in a period of 3650-120 days before the operation date. Pearson chi-squared test for cancer stage was calculated. Odds Ratio (OR) with 95% confidence interval (CI) for having had a palliative vs an intended curative aim of the operative treatment for CRC patients (cohort 1), and for having an oncological treatment for each cancer site CC or RC (cohort 2 and 3) in patients with and without a psychiatric history was estimated. We adjusted the OR for: age, gender, comorbidity index, cancer stage, socio-economic position group, and educational level.
resultsA higher cancer stage at the time of operation in patients with psychiatric disorders compared with patients without such a history was seen and may possibly point towards a delay in the diagnosis or in the treatment of CC in patients with psychiatric disorders. They also had decreased adjusted OR for having an oncological treatment, OR 0.55, 95% CI (0.40-0.76)), which was not explained by cancer stage. For patients with RC no difference was seen.
conclusionsAttention for CC patients with pre-existing serious psychiatric disorders is recommended.
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