Evidence map›Paper›PMID 30373421›Full record

SynthesisJournal of the American Heart Association2018

Off- Versus On-Pump Coronary Surgery and the Effect of Follow-Up Length and Surgeons' Experience: A Meta-Analysis.

Mario Gaudino, Umberto Benedetto, Faisal Bakaeen, Mohamed Rahouma, Derrick Y Tam, Ahmed Abouarab, Antonino Di Franco, Jeremy Leonard, Adham Elmously, John D Puskas and 4 more

Abstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Impact of on-pump and off-pump coronary artery bypass grafting on 10-year mortality versus percutaneous coronary intervention.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023
    Article
  11. Review
  12. Intensive care unit length of stay and mortality comparison between on-pump and off-pump coronary artery bypass graft: a retrospective study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
  13. Off pump Versus On pump Coronary Artery Bypass Grafting: Short-term Outcomes.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Intimal aortic atherosclerosis in cardiac surgery: surgical strategies to prevent embolic stroke.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2021
    Review
  19. Observational
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Mario Gaudino1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Umberto Benedetto2 Bristol Heart Institute School of Clinical Sciences University of Bristol United Kingdom.
Faisal Bakaeen3 Department of Thoracic and Cardiovascular Surgery Cleveland Clinic Cleveland OH.
Mohamed Rahouma1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Derrick Y Tam4 Schulich Heart Centre Sunnybrook Health Science University of Toronto Canada.
Ahmed Abouarab1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Antonino Di Franco1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Jeremy Leonard1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Adham Elmously1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
John D Puskas5 Department of Cardiovascular Surgery Icahn School of Medicine at Mount Sinai New York City NY.
Gianni D Angelini2 Bristol Heart Institute School of Clinical Sciences University of Bristol United Kingdom.
Leonard N Girardi1 Department of Cardio-Thoracic Surgery Weill Cornell Medicine New York City NY.
Stephen E Fremes4 Schulich Heart Centre Sunnybrook Health Science University of Toronto Canada.
David P Taggart6 Nuffield Department of Surgical Sciences University of Oxford United Kingdom.

Funding

British Heart Foundation CH/1992027/7163British Heart Foundation PG/11/19/28827British Heart Foundation PG/13/9/29990Medical Research Council MR/J015350/1
6 · The paper itself

Abstract

Background The debate on the relative benefits of off-pump and on-pump coronary artery bypass surgery ( OPCABG and ONCABG ) is still open. We aimed to provide an updated and complete summary of the evidence on the differences between OPCABG and ONCABG and to explore whether the length of the follow-up and the surgeons' experience in OPCABG modify the comparative results. Methods and Results All randomized clinical trials comparing OPCABG and ONCABG were included. Primary outcome was follow-up mortality. Secondary outcomes were operative mortality, perioperative stroke, perioperative myocardial infarction, and late repeated revascularization. Subgroup analyses were performed based on the length of the follow-up and the percentage of crossover from the OPCABG group (used as a surrogate of surgeon experience with OPCABG ). One hundred four trials were included (20 627 patients, OPCABG : 10 288; ONCABG : 10 339). Weighted mean follow-up time was 3.7 years (range 1-7.5 years). OPCABG was associated with a higher risk of follow-up mortality (incidence rate ratio 1.11, 95% confidence interval 1.00-1.23, P=0.05). The difference was significant only for trials with mean follow-up of ≥3 years and for studies with a crossover rate of ≥10%. There was a trend toward lower risk of perioperative stroke and higher need for late repeated revascularization in the OPCABG arm. Conclusions OPCABG is associated with a higher incidence of incomplete revascularization, an increased need for repeated revascularization, and decreased midterm survival compared with ONCABG . Surgeon inexperience in OPCABG is associated with late mortality.

Indexed as

Clinical CompetenceThoracic SurgeryCoronary Artery BypassCoronary Artery Bypass, Off-PumpCoronary Artery DiseaseFollow-Up StudiesHumansRandomized Controlled Trials as TopicTime Factorscoronary artery bypasscoronary artery bypass graftingmyocardial revascularizationoff‐pump coronary artery bypass graftingoff‐pump surgeryrevascularization

Identifiers

PMID30373421
PMCPMC6404195

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.