ArticleSensors (Basel, Switzerland)2018
Guiding Ketogenic Diet with Breath Acetone Sensors.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 87 citations in OpenAlex.
- Correlation Between Breath Acetone and Ketone Bodies in Blood and Urine Among Individuals with Different Glycometabolic Statuses Based on PTR-TOF-MS.Diagnostics (Basel, Switzerland) · 2026Article
- Challenges and opportunities of wearable molecular sensors in endocrinology and metabolism.Nature reviews. Endocrinology · 2026Review
- Associations between breath acetone overnight dynamics and obstructive sleep apnea manifestations.BMC pulmonary medicine · 2025Article
- Progress and Strategies of Wearable Sensors in Human Health Monitoring Based on Physiological, Biochemical, and Environmental Signals.ACS omega · 2025Review
- Selectivity in Chemiresistive Gas Sensors: Strategies and Challenges.Chemical reviews · 2025Review
- Update on Measuring Ketones.Journal of diabetes science and technology · 2024Review
- A Novel Acetone Sensor for Body Fluids.Biosensors · 2023Article
- Handheld device quantifies breath acetone for real-life metabolic health monitoring.Sensors & diagnostics · 2023Article
- A Strategy to Enhance Humidity Robustness of p-Type CuO Sensors for Breath Acetone Quantification.Small science · 2023Article
- Research progress of electronic nose technology in exhaled breath disease analysis.Microsystems & nanoengineering · 2023Review
- Adherence to Low-Carbohydrate Diets in Patients with Diabetes: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Review
- Article
- Acetone Sensing and Catalytic Conversion by Pd-Loaded SnOMaterials (Basel, Switzerland) · 2021Article
- Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis.Obesity science & practice · 2021Review
- A Study on Seizure Detection of EEG Signals Represented in 2D.Sensors (Basel, Switzerland) · 2021Article
- Room-Temperature Catalyst Enables Selective Acetone Sensing.Materials (Basel, Switzerland) · 2021Article
- Monitoring Lipolysis by Sensing Breath Acetone down to Parts-per-Billion.Small science · 2021Article
- The Ketogenic Diet: Breath Acetone Sensing Technology.Biosensors · 2021Review
- Effects of Reduced Carbohydrate Intake after Sprint Exercise on Breath Acetone Level.Nutrients · 2020Article
- Breath Acetone Measurement-Based Prediction of Exercise-Induced Energy and Substrate Expenditure.Sensors (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Ketogenic diet (KD; high fat, low carb) is a standard treatment for obesity, neurological diseases (e.g., refractory epilepsy) and a promising method for athletes to improve their endurance performance. Therein, the level of ketosis must be regulated tightly to ensure an effective therapy. Here, we introduce a compact and inexpensive breath sensor to monitor ketosis online and non-invasively. The sensor consists of Si-doped WO₃ nanoparticles that detect breath acetone selectively with non-linear response characteristics in the relevant range of 1 to 66 ppm, as identified by mass spectrometry. When tested on eleven subjects (five women and six men) undergoing a 36-h KD based on the Johns Hopkins protocol, this sensor clearly recognizes the onset and progression of ketosis. This is in good agreement to capillary blood β-hydroxybutyrate (BOHB) measurements. Despite similar dieting conditions, strong inter-subject differences in ketosis dynamics were observed and correctly identified by the sensor. These even included breath acetone patterns that could be linked to low tolerance to that diet. As a result, this portable breath sensor represents an easily applicable and reliable technology to monitor KD, possibly during medical treatment of epilepsy and weight loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.