Evidence map›Paper›PMID 30373151›Full record

ArticleInternational journal of environmental research and public health2018

Agent-Based Modeling for Super-Spreading Events: A Case Study of MERS-CoV Transmission Dynamics in the Republic of Korea.

Yunhwan Kim, Hohyung Ryu, Sunmi Lee

Abstract read
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Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

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25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  11. A chemical engineer's take of COVID-19 epidemiology.AIChE journal. American Institute of Chemical Engineers · 2021
    Article
  12. Article
  13. Time-dependent heterogeneity leads to transient suppression of the COVID-19 epidemic, not herd immunity.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Review
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Yunhwan KimDivision of Media Communication, Hankuk University of Foreign Studies, Seoul 02450, Korea. yunhwankim2@gmail.com.ORCID 0000-0003-1138-6802
Hohyung RyuDepartment of Applied Mathematics, Kyung Hee University, Yongin 446-701, Korea. kyinr108@gmail.com.
Sunmi LeeDepartment of Applied Mathematics, Kyung Hee University, Yongin 446-701, Korea. sunmilee@khu.ac.kr.ORCID 0000-0003-1126-0660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Super-spreading events have been observed in the transmission dynamics of many infectious diseases. The 2015 MERS-CoV outbreak in the Republic of Korea has also shown super-spreading events with a significantly high level of heterogeneity in generating secondary cases. It becomes critical to understand the mechanism for this high level of heterogeneity to develop effective intervention strategies and preventive plans for future emerging infectious diseases. In this regard, agent-based modeling is a useful tool for incorporating individual heterogeneity into the epidemic model. In the present work, a stochastic agent-based framework is developed in order to understand the underlying mechanism of heterogeneity. Clinical (i.e., an infectivity level) and social or environmental (i.e., a contact level) heterogeneity are modeled. These factors are incorporated in the transmission rate functions under assumptions that super-spreaders have stronger transmission and/or higher links. Our agent-based model has employed real MERS-CoV epidemic features based on the 2015 MERS-CoV epidemiological data. Monte Carlo simulations are carried out under various epidemic scenarios. Our findings highlight the roles of super-spreaders in a high level of heterogeneity, underscoring that the number of contacts combined with a higher level of infectivity are the most critical factors for substantial heterogeneity in generating secondary cases of the 2015 MERS-CoV transmission.

Indexed as

EpidemicsBasic Reproduction NumberCoronavirus InfectionsIncidenceMiddle East Respiratory Syndrome CoronavirusModels, TheoreticalMonte Carlo MethodRepublic of KoreaStochastic Processes2015 MERS-CoVagent-based modelsbasic reproduction numberisolation interventionssuper-spreading events

Identifiers

PMID30373151
PMCPMC6265857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.