Evidence map›Paper›PMID 30373103›Full record

ArticleFoods (Basel, Switzerland)2018

Açai (

Raquel Martins Martinez, Deborah de Almeida Bauer Guimarães, Camila Ramos Berniz, Joel Pimentel de Abreu, Ana Paula Machado da Rocha, Roberto Soares de Moura, Angela Castro Resende, Anderson Junger Teodoro

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Effect ofBiology · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Açaí (Nutrients · 2023
    Review
  11. Article
  12. Extract ofFrontiers in cellular neuroscience · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Açai (Molecules (Basel, Switzerland) · 2021
    Article
  17. Article
  18. The Use ofBiomolecules · 2020
    Review
  19. Broccoli (Foods (Basel, Switzerland) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Raquel Martins MartinezNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. raquelm.martinez@hotmail.com.
Deborah de Almeida Bauer GuimarãesNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. deborahbauervp@gmail.com.
Camila Ramos BernizNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. camila.rberniz@hotmail.com.
Joel Pimentel de AbreuNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. pimenabreu@gmail.com.ORCID 0000-0003-2994-7823
Ana Paula Machado da RochaDepartment of Physiological Sciences, Institute of Biomedicine Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rua Frei Caneca, 94, Rio de Janeiro CEP 20211-040, Brazil. ana.rocha@unirio.br.
Roberto Soares de MouraDepartment of Pharmacology, Institute of Biology, Universidade Estadual do Rio de Janeiro (UERJ), Av 28 de Setembro, n° 87, Rio de Janeiro CEP 20551-030, Brazil. robertosoaresdemoura@gmail.com.
Angela Castro ResendeDepartment of Pharmacology, Institute of Biology, Universidade Estadual do Rio de Janeiro (UERJ), Av 28 de Setembro, n° 87, Rio de Janeiro CEP 20551-030, Brazil. angelacr@uerj.br.
Anderson Junger TeodoroNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. atteodoro@gmail.com.ORCID 0000-0002-0949-9528
Universidade Federal do Estado do Rio de Janeiro · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro 228434 and 227094
6 · The paper itself

Abstract

Açai fruit has been studied for its antioxidant properties, with positive feedback against many diseases, including cancer. Although açai seeds are not edible, their composition has been studied in order to find new applications and reduce garbage generation. This study aimed to evaluate the cytotoxic effects and impacts on the cell cycle and apoptosis of açai seed extract (ASE) on human lung carcinoma cell line (A549). Antioxidant activity of açai seed extract (ASE) was measured by DPPH assay, Trolox Equivalent Antioxidant Capacity (ABTS/TEAC), Ferric Reducing Ability (FRAP) and Oxygen radical absorbance capacity (ORAC) assays. Human lung carcinoma cell viability (A549) was monitored by MTT assay method and the effects on cell cycle and apoptosis were measured by flow cytometry. The results indicate high antioxidant activity in ASE and high values of total phenolic compounds (37.08 ± 8.56 g gallic acid/100 g). The MTT assay showed a maximum decrease (72.07%) in the viability of A549 cells after 48 h treatment with ASE (200 µg/mL). Flow cytometer analysis revealed that ASE increased the percentage of cells in G0/G1 phase and promoted a high increase of apoptotic cells when compared to the untreated cells. The present study suggests that ASE has a high antioxidant capacity and may have a protective effect against lung cancer.

Indexed as

açaiantioxidantbioactive compoundslung cancer

Identifiers

PMID30373103
PMCPMC6262440
OpenAlexW2898334336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.